therapeutic action: hypoglycemic

Functional Components from the Liquid Fermentation of Edible and Medicinal Fungi and Their Food Applications in China

Mushroom mycelium grown in liquid fermentation produces many beneficial compounds like polysaccharides and proteins that support immune function and may help fight cancer and oxidative stress. These fermented mushroom products can be added to foods, beverages, and health supplements to boost their nutritional value and health benefits. Studies show that fermented mushroom mycelium sometimes contains higher levels of beneficial compounds compared to whole mushroom fruiting bodies, making it a promising ingredient for functional foods and health products.

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Olive mill solid waste induces beneficial mushroom-specialized metabolite diversity revealed by computational metabolomics strategies

This study shows how adding olive mill waste to mushroom growing substrate can increase beneficial compounds in mushrooms while reducing harmful toxins. Researchers grew two types of edible mushrooms (lion’s mane and king oyster) on substrate containing different amounts of olive mill waste and used advanced chemical analysis to identify how the waste affected the mushrooms’ medicinal compounds. Adding olive mill waste increased healthy compounds like hericenones and erinacerins while decreasing toxic enniatin compounds, potentially creating safer and more nutritious mushrooms for consumers.

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The Antioxidant Properties of Mushroom Polysaccharides can Potentially Mitigate Oxidative Stress, Beta-Cell Dysfunction and Insulin Resistance

This research review explores how mushroom compounds called polysaccharides may help manage diabetes by reducing harmful stress on cells caused by high glucose levels. Scientists found that 104 different mushroom polysaccharides have anti-diabetic properties and can protect insulin-producing cells in the pancreas. These natural compounds show promise as a complementary treatment to conventional diabetes medications, potentially with fewer side effects than synthetic drugs.

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The Role of Wolfiporia cocos (F. A. Wolf) Ryvarden and Gilb. Polysaccharides in Regulating the Gut Microbiota and Its Health Benefits

Wolfiporia cocos, a fungus used in traditional Chinese medicine for over 2000 years, contains polysaccharides that act as prebiotics to improve gut health. These polysaccharides promote the growth of beneficial bacteria while inhibiting harmful ones, increase production of healthy metabolites, and strengthen the intestinal barrier. By improving gut microbiota composition, these polysaccharides can help prevent and treat various diseases including obesity, diabetes, and inflammatory conditions.

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The impact of continuous cultivation of Ganoderma lucidum on soil nutrients, enzyme activity, and fruiting body metabolites

This study examined how growing Ganoderma lucidum (a medicinal mushroom) on the same land for two consecutive years affects the soil and the mushroom’s beneficial compounds. Researchers found that continuous cultivation depleted soil nutrients and reduced enzyme activity, particularly in the top layer of soil. The mushrooms grown in the first year had more beneficial compounds than those grown in the second year, with differences linked to changes in soil quality and microbial activity.

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Ultrasound-assisted extraction of neuroprotective antioxidants from Ganoderma lucidum

This research studied how to best extract healing compounds from the reishi mushroom (Ganoderma lucidum), an important traditional Chinese medicine. Using advanced extraction techniques and computer modeling, scientists identified optimal conditions that doubled the amount of beneficial antioxidants obtained compared to conventional methods. They then tested these extracts on nerve cells in the laboratory, demonstrating that the extracts effectively protected cells from oxidative damage and injury.

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Structural Elucidation, Modification, and Structure-Activity Relationship of Polysaccharides in Chinese Herbs: A Review

This comprehensive review explains how the structure of plant polysaccharides from Chinese herbs determines their healing properties. The authors discuss various laboratory methods to identify polysaccharide structures and explain how chemical modifications can enhance their beneficial effects like boosting immunity and fighting tumors. The review provides guidance for researchers developing new polysaccharide-based medicines and shows that finding the right molecular size and chemical composition is key to maximizing therapeutic benefits.

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Isolation Techniques, Structural Characteristics, and Pharmacological Effects of Phellinus Polysaccharides: A Review

This review examines how scientists extract and study beneficial compounds called polysaccharides from a medicinal fungus called Phellinus. These polysaccharides show promise in fighting cancer, reducing inflammation, and boosting immune function. Different extraction methods affect the quality and effectiveness of these compounds, and researchers are working to optimize these techniques for better therapeutic applications.

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Research progress of edible mushroom polysaccharide-metal trace element complexes

This research reviews how edible mushroom polysaccharides can be combined with essential metals like iron, selenium, and zinc to create health-boosting supplements. These complexes improve how our bodies absorb and use these important minerals, offering benefits like better immune function, antioxidant protection, and potential cancer-fighting properties. Scientists are studying different ways to make these complexes and testing their effectiveness for treating various health conditions.

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Comparative Metabolite Profiling Between Cordyceps sinensis and Other Cordyceps by Untargeted UHPLC-MS/MS

This research compares the chemical compounds found in authentic Cordyceps sinensis with four similar but different Cordyceps species to identify which ones are real. Using advanced laboratory techniques, scientists detected thousands of chemical differences between the species. They found that genuine C. sinensis contains higher levels of specific beneficial compounds like nucleosides and certain fatty acids. These findings help consumers and merchants distinguish authentic Cordyceps from counterfeit products and lower-quality substitutes.

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