hepatoprotection – mycolab.ai

Ganoapplanilactone C from Ganoderma applanatum Ameliorates Metabolic Dysfunction-Associated Steatotic Liver Disease via AMPK/mTOR-Mediated Lipid Regulation in Zebrafish

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Researchers found that a compound called ganoapplanilactone C from the medicinal mushroom Ganoderma applanatum can protect the liver from fat accumulation and damage caused by high-fat diets. In zebrafish studies, this compound worked better than a common cholesterol drug at reducing liver fat and improving liver health. The compound appears to work by activating a protein called AMPK that helps regulate how the body processes fats and reduces inflammation.

Development and preliminary mechanistic analysis of compound effervescent hepatoprotective granules

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Researchers developed a new health product combining three medicinal plants to protect the liver from injury. The mixture contains effective compounds that reduce liver inflammation, fight harmful oxidative stress, and protect liver cells from damage. Studies in rats showed the product improved liver function and reduced markers of liver damage, suggesting it could be useful for preventing and treating liver injuries caused by drugs, alcohol, or toxins.

Comparative Analysis of Main Agronomic Traits of Different Pleurotus giganteus Germplasm Resources

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Scientists studied 15 different varieties of giant oyster mushrooms to understand their growth characteristics and quality traits. They tested how fast the mushroom threads grow at different temperatures, measured the size and weight of the mushrooms produced, and calculated how efficiently each variety converts growing material into edible mushrooms. Strain No. 9 performed best with the largest yields and highest quality mushrooms, while different strains showed distinct characteristics that could be used to develop superior commercial varieties.

Exploring Therapeutic Potential of Pleurotus ostreatus and Agaricus bisporus Mushrooms against Hyperlipidemia and Oxidative Stress Using Animal Model

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Oyster and white button mushrooms may help lower cholesterol and protect against heart disease. In a study using rats with high cholesterol, mushroom extracts reduced harmful cholesterol levels and improved the body’s natural defense against oxidative damage. These common, affordable mushrooms contain beneficial compounds that could be incorporated into diets as a natural way to support heart health and manage cholesterol.

A Review of Research Progress on the Microbial or Enzymatic Degradation and Mechanism of Aflatoxin B1

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Aflatoxin B1 is a dangerous toxin found in contaminated cereals and food products that can cause serious diseases including liver cancer. Scientists have discovered that certain bacteria and fungi can naturally break down this toxin into less harmful substances through their enzymes. This review summarizes different microorganisms and enzymes that can degrade aflatoxin B1, explaining how they work and what safe products they create, offering hope for safer food storage and treatment.

Edible Fungi Melanin: Recent Advances in Extraction, Characterization, Biological Activity and Applications

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Melanin from edible mushrooms like black wood ear and reishi offers a natural, sustainable alternative to synthetic melanins with impressive health benefits. These mushroom melanins demonstrate powerful antioxidant and antibacterial properties, protect against radiation damage, and can help maintain liver health. New extraction methods using special solvents are making it easier to obtain pure melanin from mushrooms efficiently, opening doors for its use in food, cosmetics, and medicines.

Inonotus obliquus aqueous extract prevents histopathological alterations in liver induced by environmental toxicant Microcystin

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This research shows that Chaga mushroom extract can protect the liver from damage caused by microcystin, a toxic chemical produced by cyanobacteria in water. When mice were exposed to microcystin, their livers became damaged, but treating them with Chaga mushroom extract restored normal liver function and prevented cell death. The study suggests Chaga mushroom could be used as a natural supplement to prevent liver toxicity from environmental pollutants.

The effect of chitosan supplementation on liver function, hepatic steatosis predictors, and metabolic indicators in adults with non-alcoholic fatty liver disease: a randomized, double-blinded, placebo-controlled, clinical trial

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This study tested whether taking chitosan supplements (a type of dietary fiber) helps people with fatty liver disease. Over 8 weeks, participants taking chitosan along with a calorie-reduced diet lost more weight, reduced their waist size, and showed improvement in liver enzyme levels compared to those taking placebo. However, the supplement did not significantly improve cholesterol, blood sugar, or other metabolic markers at the dose tested.

Comparative Efficacy of Antrodia cinnamomea on Liver Function Biomarkers in Mice and Rats: A Network Meta-Analysis

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This study compared different extracts from a medicinal mushroom called Antrodia cinnamomea to see which ones work best for protecting liver health. Researchers analyzed data from multiple animal studies and found that extracts rich in compounds called triterpenoids were the most effective at improving liver function and reducing inflammation. The findings suggest that this mushroom could potentially become a natural treatment option for liver disease in the future.

therapeutic action: hepatoprotection