therapeutic action: gut barrier integrity enhancement

Quercetin hybrid-hydrogel microparticles modulate gut microbiota and improve memory in an antibiotic-induced dysbiosis rat model

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A natural quercetin supplement formulated with fenugreek fiber was tested on rats with antibiotic-damaged gut bacteria. The supplement successfully restored healthy gut bacteria diversity, reduced gut inflammation, and improved memory performance. These benefits likely work through the gut-brain connection, where healthy bacteria produce beneficial chemicals that support brain function and reduce inflammation.

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Triacetin and a Mushroom Blend Restore Butyrate Production by IBS Microbiomes Ex Vivo, Thus Promoting Barrier Integrity

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Researchers tested two natural products—triacetin and a mushroom blend—to see if they could help people with IBS by improving their gut bacteria and strengthening their intestinal lining. Both products successfully increased beneficial short-chain fatty acids and improved barrier integrity, with triacetin having the added advantage of producing less uncomfortable gas. These findings suggest these products could offer a new dietary approach to managing IBS symptoms.

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Marine-Derived Enterococcus faecalis HY0110 as a Next-Generation Functional Food Probiotic: Comprehensive In Vitro and In Vivo Bioactivity Evaluation and Synergistic Fermentation of Periplaneta americana Extract Powder

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Scientists discovered a beneficial bacteria called Enterococcus faecalis HY0110 from bluefin tuna that could help protect gut health and fight harmful pathogens better than current probiotics. This marine bacteria produces important compounds like acetic acid that kill disease-causing bacteria, reduce inflammation in inflammatory bowel disease, and even slows cancer cell growth. When fermented with cockroach powder, it creates powerful health-boosting compounds that could make functional foods more effective for managing digestive diseases and supporting overall wellness.

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