therapeutic action: Gene deletion reduces pathogenic fungal virulence and growth

VdPAT1 encoding a pantothenate transporter protein is required for fungal growth, mycelial penetration and pathogenicity of Verticillium dahliae

Verticillium dahliae is a destructive fungus that causes a wilting disease in cotton crops. Researchers found that a specific protein (VdPAT1) that helps the fungus absorb vitamin B5 is critical for its survival and ability to infect cotton plants. When they disabled this protein, the fungus grew poorly, couldn’t penetrate plant tissues effectively, and became much less virulent, suggesting this protein could be a target for controlling the disease.

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