therapeutic action: fungal growth inhibition

Postharvest Disease Management of ‘Akizuki’ Pear in China: Identification of Fungal Pathogens and Control Efficacy of Chlorine Dioxide

Researchers identified four types of fungi that cause rot in ‘Akizuki’ pears during storage: Alternaria alternata, Diaporthe eres, and two types of Penicillium. They tested chlorine dioxide gas as a treatment and found it effectively stopped the fungi from growing without harming the fruit. This discovery offers a safer, more environmentally friendly alternative to traditional fungicide chemicals for keeping stored pears fresh longer.

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Molecular epidemiology, diversity, and antifungal susceptibility profiles of clinical and environmental mucorales: a five-year multicenter study in Iran (2018–2023)

This research examined dangerous mold infections (Mucormycosis) that became more common after COVID-19. Scientists identified the types of molds causing these infections in Iran by testing 116 patient samples and 65 soil samples from across the country. They tested these molds against 13 different antifungal medications to find which drugs work best. The results showed that amphotericin B and posaconazole were the most effective medications, and patient samples were more susceptible to these drugs than environmental soil samples.

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Antifungal activity of zinc oxide nanoparticles (ZnO NPs) on Fusarium equiseti phytopathogen isolated from tomato plant in Nepal

Researchers in Nepal developed a natural way to fight tomato plant diseases by creating tiny zinc oxide nanoparticles from tea leaves. These nanoparticles successfully stopped the growth of a harmful fungus called Fusarium equiseti that was damaging tomato crops. Unlike chemical fungicides that can harm the environment, this eco-friendly approach damaged the fungus’s cell structures without posing risks to surrounding ecosystems, offering farmers a safer way to protect their crops.

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Endocarditis caused by Scopulariopsis brevicaulis with disseminated emboli and multiple vascular aneurysms: A case report and literature review

A 61-year-old man with a prosthetic aortic valve developed a rare fungal infection caused by Scopulariopsis brevicaulis, a mold usually associated with nail infections. The infection spread throughout his body, causing multiple strokes and aneurysms that required emergency surgery and treatment with various antifungal medications. This case highlights the serious complications that can occur when this typically harmless fungus invades the heart and demonstrates the challenges doctors face in treating such rare infections, as the fungus was resistant to many common antifungal drugs.

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Transcriptome and metabolome profiling reveal the inhibitory effects of food preservatives on pathogenic fungi

This research tested three common food preservatives to see how well they stop harmful molds from growing on fruits and vegetables. Scientists found that all three preservatives worked well at different concentrations, with sec-butylamine being particularly effective. By studying the genes and chemical changes in treated fungal cells, they discovered that these preservatives work by damaging the mold’s cell walls and disrupting how it processes sugars, essentially starving and weakening the fungal cells.

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Antagonistic Potential of Agro-Industrial Byproduct–Derived Lactic Acid Bacteria Against Mycotoxigenic Aspergillus flavus and Fusarium verticillioides

Researchers discovered that certain lactic acid bacteria found in food waste products can effectively prevent the growth of harmful fungi and block the production of dangerous mycotoxins. These bacteria work through multiple mechanisms including acidification and production of protective compounds. The findings suggest these natural bacteria could be used as safe, sustainable alternatives to chemical fungicides in food preservation and safety.

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Nano Emulsion of Essential Oils Loaded in Chitosan Coating for Controlling Anthracnose in Tomatoes (Solanum lycopersicum) During Storage

Researchers developed a natural coating made from chitosan (a biopolymer) and thyme essential oil nano particles to protect tomatoes from a fungal disease called anthracnose during storage. When applied to tomatoes, this coating reduced disease occurrence by 50%, outperforming the commercial fungicide currently used. This eco-friendly solution offers a sustainable alternative to synthetic chemical treatments while maintaining tomato quality for longer periods.

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Essential Oils as an Antifungal Alternative to Control Several Species of Fungi Isolated from Musa paradisiaca: Part II

Bananas often develop fungal infections during storage that reduce their quality. Researchers tested whether essential oils from common herbs and spices like cinnamon, clove, and oregano could prevent these fungal infections. The study found that cinnamon, clove, and oregano oils effectively stopped fungal growth at higher concentrations, offering a natural alternative to chemical fungicides that could help keep bananas fresh longer without synthetic chemicals.

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Simplicillium sinense sp. nov., a novel potential pathogen of tinea faciei

Researchers identified a new fungal species called Simplicillium sinense that caused a facial skin infection (tinea faciei) in a 46-year-old man with diabetes. The fungus was resistant to most common antifungal medications but responded well to terbinafine treatment. This is the first reported case of a Simplicillium infection causing facial ringworm, expanding our understanding of rare fungal pathogens.

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Effect of Pseudomonas protegens EMM-1 Against Rhizopus oryzae in Interactions with Mexican Autochthonous Red Maize

Mexican red maize, an important traditional crop, is threatened by a fungus called Rhizopus oryzae that causes root damage and wilting. Researchers found that a beneficial bacterium, Pseudomonas protegens EMM-1, can effectively stop this fungal infection and help maize plants grow better. Tests showed the bacterium reduced fungal growth by over 80% and improved plant root development when grown together with the fungus.

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