therapeutic action: fungal growth inhibition

Neem Essential Oil as an Antifungal Agent against Phyllosticta citricarpa

Citrus fruits are susceptible to a serious fungal disease called black spot that prevents them from being exported to certain countries. This study tested neem oil, a natural plant extract, as a replacement for chemical fungicides currently used to clean citrus fruits. The researchers found that neem oil was just as effective as the standard copper-based treatments at killing the fungus and preventing the disease, and it worked by breaking down the fungus cell membranes. This natural alternative could help farmers and fruit companies maintain food safety while using more eco-friendly solutions.

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Endogenous Endophthalmitis: An underestimated serious complication in patients with disseminated fusariosis

An 18-year-old leukemia patient developed a serious fungal eye infection from Fusarium during cancer treatment. The infection spread through the bloodstream to both eyes, causing serious inflammation and vision loss. Doctors treated it with multiple antifungal medications injected directly into the eyes along with systemic medication, which controlled the infection but unfortunately the patient’s vision was significantly affected. This case highlights how rare but serious eye infections can occur in cancer patients with weakened immune systems.

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Biocontrol of Seedborne Fungi on Small-Grained Cereals Using Bacillus halotolerans Strain B33

Researchers discovered that a bacterium called Bacillus halotolerans strain B33 can effectively prevent harmful fungi from damaging cereal seeds like wheat, barley, oats, and rye. When seeds were treated with this beneficial bacterium, it successfully eliminated or greatly reduced three dangerous fungal pathogens while also helping the seeds germinate better. This natural approach offers a promising environmentally-friendly alternative to chemical fungicides for protecting grain crops.

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Essential Oils as an Antifungal Alternative to Control Several Species of Fungi Isolated from Musa paradisiaca: Part III

Researchers tested six essential oils from common culinary herbs to control fungal diseases that damage bananas after harvest. Thyme, cinnamon, and oregano oils were most effective at preventing fungal growth at concentrations between 600-1000 parts per million. These natural oils could replace synthetic fungicides in banana storage facilities, providing a safer, more environmentally friendly approach to preserving fruit quality.

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Exo-metabolome profiling of soybean endophytes: a road map of antagonism against Fusarium oxysporum

Scientists discovered that certain beneficial bacteria living inside soybean roots can protect the plant from a harmful fungus that causes root rot and reduces crop yield. By analyzing the chemical compounds these bacteria produce, researchers identified specific antifungal substances that kill or inhibit the pathogenic fungus. These findings suggest that instead of using harmful chemical fungicides, farmers could use these beneficial bacteria as a natural, environmentally-friendly way to protect soybean crops and improve agricultural sustainability.

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Antifungal Activity of Selected Naphthoquinones and Their Synergistic Combination with Amphotericin B Against Cryptococcus neoformans H99

Researchers tested five compounds called naphthoquinones for their ability to fight a dangerous fungal infection called cryptococcosis. They found that one compound called 2-MNQ works especially well when combined with the standard antifungal drug amphotericin B, making the treatment more effective. This discovery could lead to better treatments for people with weakened immune systems who are vulnerable to this infection.

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Antifungal effect of soil Bacillus bacteria on pathogenic species of the fungal genera Aspergillus and Trichophyton

Scientists found that certain bacteria naturally occurring in soil can effectively kill harmful fungi that cause infections in humans. By isolating and testing different Bacillus bacteria species, researchers discovered that some were even more effective at inhibiting fungal growth than commonly used antifungal medications. This finding suggests a promising natural alternative to combat fungal infections, especially as many fungi are becoming resistant to traditional antifungal drugs.

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Postharvest Disease Management of ‘Akizuki’ Pear in China: Identification of Fungal Pathogens and Control Efficacy of Chlorine Dioxide

‘Akizuki’ pears are a popular fruit in China but often develop rot diseases during storage, causing significant economic losses. Researchers identified four types of fungi responsible for this rot and tested chlorine dioxide gas as a treatment. The study found that chlorine dioxide effectively kills these fungi by damaging their cell membranes and works as well as commercial fungicides, offering a safer alternative for preserving pears without harmful chemical residues.

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Native Bacteria Are Effective Biocontrol Agents at a Wide Range of Temperatures of Neofusicoccum parvum, Associated with Botryosphaeria Dieback on Grapevine

Scientists discovered that native bacteria from Chile, particularly Pseudomonas strains, can effectively control a serious fungus that damages grapevines. These bacteria work across a range of temperatures and successfully reduced fungal growth both in laboratory tests and in actual vineyards. This discovery offers a natural, environmentally-friendly alternative to chemical fungicides for protecting grape crops.

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Isolation and Biological Control of Colletotrichum sp. Causing Anthracnosis in Theobroma cacao L. in Chiapas, Mexico

Cacao farmers in Mexico’s Chiapas region face serious crop losses from anthracnose, a fungal disease caused by Colletotrichum. Researchers found a beneficial bacterium called Paenibacillus sp. NMA1017 that can suppress this disease as effectively as commercial fungicide alternatives. By testing this natural biocontrol agent both in the laboratory and on actual cacao farms, they demonstrated it could reduce disease occurrence from 65% down to just 12-20%, offering farmers a sustainable alternative to chemical treatments.

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