fungal growth inhibition

Decursin, Identified via High-Throughput Chemical Screening, Enhances Plant Disease Resistance via Two Independent Mechanisms

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Researchers identified a natural compound called decursin from angelica plants that helps plants fight off dangerous fungal infections in two ways: it strengthens the plant’s own immune system and directly kills the fungal pathogens. This dual-action approach makes decursin a promising natural alternative to synthetic fungicides for protecting crops like wheat and tomatoes from diseases. The compound shows particular promise because it comes from plants, breaks down easily in the environment, and is more effective than other natural antimicrobial compounds currently used in agriculture.

Inhibitory Activity of Shrimp Waste Extracts on Fungal and Oomycete Plant Pathogens

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Researchers discovered that waste from shrimp processing can be converted into a natural fungicide that effectively kills plant-damaging fungi and mold. When applied to oranges, lemons, and apples artificially infected with mold, the shrimp waste extract significantly reduced rot and fruit damage. This finding is important because it offers a more environmentally friendly alternative to chemical fungicides while helping reduce the massive amounts of shrimp processing waste that typically end up in landfills or oceans.

Streptomyces-Based Bioformulation to Control Wilt of Morchella sextelata Caused by Pestalotiopsis trachicarpicola

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Morel mushrooms are delicious and nutritious but are threatened by a fungal disease that can destroy up to 80% of crops. Scientists discovered that two beneficial bacteria species (Streptomyces) from morel soil produce compounds that kill the disease-causing fungus. When applied to morel fields, these beneficial bacteria not only prevented the disease but also increased mushroom yields by about 30% compared to untreated crops, offering a natural and sustainable solution for morel farmers.

Transforming Tomato Industry By-Products into Antifungal Peptides Through Enzymatic Hydrolysis

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Researchers have found a way to turn tomato processing waste into useful antifungal compounds. By breaking down tomato seed proteins using enzymes, they created peptides that can prevent harmful fungi like Fusarium from growing on crops. This discovery helps reduce food waste while providing a natural alternative to chemical pesticides for protecting tomato and grain crops.

Native Bacteria Are Effective Biocontrol Agents at a Wide Range of Temperatures of Neofusicoccum parvum, Associated with Botryosphaeria Dieback on Grapevine

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Researchers from Chile identified native bacteria (specifically Pseudomonas strains) that effectively prevent a destructive fungal disease affecting grapevines. These bacteria can work across a wide range of temperatures and significantly reduce fungal growth both in laboratory tests and in actual vineyard conditions. This discovery offers an environmentally friendly alternative to chemical fungicides for protecting grapevines, particularly important as younger vines appear more vulnerable to infection.

Mesoporous silica and vegetal extracts combined as sustainable stone heritage protection against biodeterioration

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Researchers developed an eco-friendly method to protect historic stone buildings and sculptures from fungal damage. They trapped natural plant oils (from oregano and thyme) inside tiny nano-containers made of silica, which slowly releases the antimicrobial compounds over time. When tested on marble samples, this coating prevented fungal growth for two months without harmful chemicals, making it safe for both the environment and workers preserving cultural heritage.

Antifungal Efficacy of Luliconazole-Loaded Nanostructured Lipid-Carrier Gel in an Animal Model of Dermatophytosis

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Researchers developed a new antifungal gel containing luliconazole loaded into tiny lipid nanoparticles to treat stubborn fungal skin infections caused by Trichophyton indotineae that resist standard terbinafine treatment. Testing in guinea pigs showed this new nanoformulation penetrated skin better and cleared infections faster (21 days) compared to regular luliconazole gel (28 days) and terbinafine-treated animals. The nanoparticle delivery system improved the drug’s ability to reach infected skin layers and showed no harmful side effects, offering promise for treating resistant fungal infections in patients.

Inhibition of Fusarium oxysporum growth in banana by silver nanoparticles: In vitro and in vivo assays

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Bananas are threatened by a fungal disease called Fusarium wilt that damages crops worldwide. Scientists tested tiny silver particles called nanoparticles as a treatment for this disease on banana plants. The treatment successfully reduced disease by about 68% when applied to the roots, showing promise as an alternative to traditional fungicides for protecting banana crops.

Pathogen Enzyme-Mediated Alkoxyamine Homolysis as a Killing Mechanism of Aspergillus fumigatus

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Researchers have developed a new type of antifungal drug that uses the fungus’s own enzymes against it. The drug is inactive until it encounters an enzyme produced by Aspergillus fumigatus, where it releases toxic molecules that kill the fungus. Importantly, this approach works against both normal and drug-resistant strains of the fungus, offering hope for treating serious fungal infections that don’t respond to current treatments.

Inhibition of Fusarium oxysporum growth in banana by silver nanoparticles: In vitro and in vivo assays

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Researchers tested silver nanoparticles as a potential cure for Fusarium wilt, a serious fungal disease that damages banana crops worldwide. Using laboratory tests and greenhouse experiments with banana plants, they found that silver nanoparticles effectively killed the fungus and reduced disease symptoms by about 68% when applied to plant roots. The study shows that this nanotechnology approach could offer a new way to protect banana plantations from this devastating disease.

therapeutic action: fungal growth inhibition