therapeutic action: Fungal cell membrane disruption

Essential Oils as an Antifungal Alternative to Control Several Species of Fungi Isolated from Musa paradisiaca: Part III

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This study tested six common essential oils (from oregano, thyme, cinnamon, clove, rosemary, and basil) to see if they could stop five types of fungi that spoil bananas after harvest. Thyme oil worked best, completely stopping fungal growth at the highest concentration tested. Cinnamon and oregano oils also worked well at moderate concentrations. These natural oils could replace synthetic fungicides and help keep bananas fresher longer during storage and transport.

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Healthcare-associated fungal infections and emerging pathogens during the COVID-19 pandemic

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During the COVID-19 pandemic, fungal infections became a major health concern, especially in hospitalized patients. Treatments for COVID-19, such as steroids and immunosuppressive drugs, weakened patients’ immune systems, making them vulnerable to serious fungal infections like those caused by Candida auris. Current antifungal medications have significant side effects and many fungi are developing resistance, so scientists are urgently seeking safer and more effective antifungal treatments.

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The In vitro Effect of Nanoliposomal Amphotericin B Against Rhizopus arrhizus Isolated From COVID-19-Associated Mucormycosis Patients

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Scientists tested a new nano-formulation of the antifungal drug amphotericin B against a dangerous fungus (Rhizopus arrhizus) that infected COVID-19 patients with mucormycosis. The nanoliposomal version of the drug worked much better than regular amphotericin B and other antifungal medications currently used, showing much lower concentrations needed to kill the fungus. This research suggests the new nano-formulation could be a more effective treatment option for patients with this serious COVID-19 related fungal infection.

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