therapeutic action: Enhanced drug delivery

Graphene nanomaterials: A new frontier in preventing respiratory fungal infections

Fungal lung infections are a serious problem, especially for people with weak immune systems. Researchers are exploring graphene nanomaterials as a new treatment approach that can deliver antifungal drugs directly to infected areas in the lungs. These tiny particles work by creating toxic stress inside fungal cells and breaking down their protective biofilms, while using smaller drug doses and causing fewer side effects than traditional treatments.

Read More »

Conjugation of a Cryptococcus neoformans-derived metalloprotease to antifungal-loaded PLGA nanoparticles treats neural cryptococcosis in an in vitro model

Researchers developed tiny nanoparticle carriers coated with a fungal enzyme that helps them cross the protective barrier around the brain. These particles were loaded with an antifungal drug to treat brain infections caused by Cryptococcus neoformans. In laboratory tests, the Mpr1-coated particles successfully penetrated the blood-brain barrier better than regular nanoparticles and were more effective at killing the fungal cells.

Read More »
Scroll to Top