therapeutic action: ego dissolution

Direct comparison of the acute effects of lysergic acid diethylamide and psilocybin in a double-blind placebo-controlled study in healthy subjects

This study directly compared two popular psychedelic drugs, LSD and psilocybin (magic mushrooms), in 28 healthy volunteers. Researchers found that these substances produce very similar mental effects when given at equivalent doses, with the main difference being that LSD lasts longer. The study establishes that about 20 milligrams of psilocybin is roughly equivalent to 100 micrograms of LSD. These findings could help guide dosing for future psychiatric treatments using these psychedelics.

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Deconstructing Psychedelic Phenomenology: A Thematic Analysis of Discrete Phases of the Psychedelic Experience

This study examined how people describe their experiences with psychedelic drugs by analyzing personal accounts shared online. Researchers found that experiences naturally fall into three phases: preparation (where knowledge and intentions matter), the actual experience (where sensory changes, mindset, and environment shape what happens), and afterward (where lasting behavioral and attitude changes occur). The study highlights how music, nature, supportive people, and clear intentions can help guide psychedelic experiences toward positive, meaningful outcomes.

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