therapeutic action: echinocandins

Renaming Candida glabrata—A case of taxonomic purity over clinical and public health pragmatism

Candida glabrata is a common yeast infection that causes serious illnesses in humans, affecting millions of people worldwide. Scientists have recently proposed renaming it to Nakaseomyces glabrata for technical taxonomic reasons. However, this article argues against the change because it would create confusion for doctors, complicate treatment instructions on medications, disrupt disease tracking systems, and make it harder for patients to understand their conditions. Keeping the familiar name Candida glabrata is more practical and helpful for patient care and public health than strict adherence to taxonomic classification rules.

Read More »

Pathogenic characterization of Phialophora submersa, a new black yeast isolated from freshwater sediments in Spain

Scientists discovered a new black yeast fungus called Phialophora submersa in Spanish river sediments and tested whether it could infect humans. Using laboratory macrophage (immune cell) models, they found that this environmental fungus exhibits pathogenic potential similar to known disease-causing Phialophora species, though at intermediate levels. The fungus showed resistance to some antifungal drugs and displayed strain-dependent ability to survive various stress conditions. This research suggests that environmental fungal species may pose unexpected health risks despite not being able to grow at normal human body temperature.

Read More »

Addressing Critical Fungal Pathogens Under a One Health Perspective: Key Insights from the Portuguese Association of Medical Mycology

This comprehensive study by Portugal’s mycology experts examines four dangerous fungi that cause severe infections: Aspergillus fumigatus, Candida auris, Candida albicans, and Cryptococcus neoformans. The research shows that Portugal’s hospitals have varying capabilities to diagnose and treat these infections, with some laboratories well-equipped and others lacking advanced diagnostic tools. The study found concerning increases in antifungal resistance and highlights that these fungi live in hospitals, water systems, soil, and even animals, emphasizing the need for integrated approaches connecting human, animal, and environmental health to better protect public health.

Read More »

Invasive Candidiasis in Contexts of Armed Conflict, High Violence, and Forced Displacement in Latin America and the Caribbean (2005–2025)

This comprehensive review examines candida fungal infections in conflict-affected areas of Latin America and the Caribbean, where wars, violence, and displacement create dangerous conditions that make infections more likely and harder to treat. In these regions, mortality from candida bloodstream infections reaches 65% or higher among displaced populations, compared to about 45-60% in regular hospitals. The main problems are lack of proper diagnostic equipment, limited access to effective antifungal medications, malnutrition, overcrowding in shelters, and the emergence of drug-resistant fungal strains.

Read More »
Scroll to Top