A 53-year-old patient developed a serious eye infection caused by a fungus called Clonostachys rosea, which had never been reported before as causing eye disease. The infection caused a painful ulcer on the cornea (the clear front part of the eye). Doctors treated the infection with antifungal medications applied as eye drops and taken as tablets, and the patient recovered well within about a month.
A 74-year-old farmer developed a serious fungal eye infection caused by Lasiodiplodia theobromae, a rare tropical fungus. Instead of requiring eye surgery, the patient was successfully treated with a combination of two antifungal medications applied as eye drops and taken orally for eight weeks. This case is significant because it’s the first documented successful medical treatment of this particular fungal infection, highlighting the importance of quick diagnosis and avoiding corticosteroid eye drops that can worsen fungal infections.
A 66-year-old man developed a severe corneal infection from a stone chip injury that didn’t improve with standard antibiotics. Doctors discovered the infection was caused by a rare plant fungus called Stemphylium lycopersici, combined with a herpes virus. Using advanced genetic testing (mNGS) to identify the exact pathogens, they prescribed targeted antifungal and antiviral medications along with a corneal transplant, successfully healing the infection and preserving his vision.