cholesterol reduction

Overcoming Solubility Challenges: Micronization of Berberine Using the GAS Antisolvent Technique

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Berberine is a traditional medicinal compound that could treat many diseases but doesn’t work well in the body because it doesn’t dissolve in water. Researchers used a special technique with pressurized carbon dioxide to break berberine into much smaller particles. This made the particles dissolve 18% better in water, which could make berberine-based medicines more effective at treating diabetes, high cholesterol, and other conditions.

A Randomized, Double-Blind, Placebo-Controlled Clinical Trial on the Effect of a Dietary Supplement Containing Dry Artichoke and Bergamot Extracts on Metabolic and Vascular Risk Factors in Individuals with Suboptimal Cholesterol Levels

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Researchers tested a daily pill combining dried extracts from artichoke and bergamot plants to see if it could improve cholesterol levels and heart health in people with elevated cholesterol. After 12 weeks, people taking the supplement showed significant improvements in cholesterol levels, triglycerides, inflammation markers, and blood vessel function compared to those taking a placebo. The supplement was safe and well-tolerated, with minimal side effects, suggesting it could be a useful natural approach for managing cholesterol and related cardiovascular risk factors.

Clinical Implementation of Sustainable Functional Foods and Nutraceuticals in Metabolic Health: A Feasibility Study

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Researchers tested a combination of special foods and supplements made from Mediterranean plants like tomatoes, pomegranates, and hazelnuts to see if they could help people with metabolic health problems. Over 4 weeks, older adults who consumed these foods daily showed improvements in muscle, bone quality, and liver health. The products tasted good and people stuck with them easily, suggesting this approach could be a practical way to improve health through diet.

Medicinal Mushrooms as Multicomponent Mixtures—Demonstrated with the Example of Lentinula edodes

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Shiitake mushrooms are more than just tasty food—they contain numerous compounds that work together to improve health. Unlike single isolated drugs, whole mushroom preparations offer multiple benefits including boosting immunity, protecting the heart, and potentially supporting cancer treatment. These mushrooms have been used safely in Asian medicine for over 2000 years and are becoming recognized worldwide for their health-promoting properties.

Use of Medicinal Mushrooms in Layer Ration

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This review discusses how medicinal mushrooms can be added to chicken feed to improve egg production and boost chicken health, offering a natural alternative to antibiotics. Several types of mushrooms like shiitake and oyster mushrooms have been shown to increase egg quality, strengthen immunity against diseases, and reduce cholesterol in eggs. These findings support the use of mushrooms as a sustainable solution for organic egg farming without compromising production or health.

Probiotic-fortified Solanum lycopersicum (tomato) juice: free or encapsulated Lactobacillus plantarum and Lactobacillus delbrueckii

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This study developed a probiotic-enriched tomato juice using beneficial bacteria wrapped in protective capsules. The encapsulated version maintained better bacterial survival, taste, and health benefits compared to unprotected bacteria during the 28-day storage period. This creates a promising non-dairy functional beverage option for health-conscious consumers seeking improved gut health and antioxidant benefits.

Enhancing Pearl oyster mushroom (Pleurotus ostreatus) performance by evaluating the influence of potassium humate and wheat straw on yield and biochemical attributes

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This study examined how adding potassium humate (a natural organic compound) to wheat straw substrate affects the growth and quality of oyster mushrooms. Researchers tested seven different amounts of potassium humate over two growing seasons and found that a moderate amount (0.5 g per 500 g straw) produced the best results, increasing both mushroom yield and nutritional value including vitamin C and beneficial sugars. Interestingly, using more potassium humate was not better, showing that balanced application is more effective than maximum supplementation for optimal mushroom production.

Bioactive Peptides from Quinoa (Chenopodium quinoa Willd.) as Modulators of the Gut Microbiome: A Scoping Review of Preclinical Evidence

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This review examines how quinoa and its protein-derived peptides can improve gut health by changing the balance of bacteria in the digestive system. Research shows that quinoa helps boost beneficial bacteria, increases diversity of microbial communities, and promotes production of butyrate, a beneficial compound that supports intestinal health. Different disease conditions show specific improvements, such as reduced harmful bacteria in colitis and better metabolic balance in obesity, suggesting quinoa could be tailored for personalized health interventions.

Bioactive Compounds and Antioxidant Activity of Boletus edulis, Imleria badia, Leccinum scabrum in the Context of Environmental Conditions and Heavy Metals Bioaccumulation

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This study examined three popular edible mushroom species from Poland to understand their nutritional benefits and safety. While all three mushrooms are rich in beneficial compounds like antioxidants and immune-boosting polysaccharides, Boletus edulis (porcini) accumulates concerning levels of cadmium from soil. The research shows these mushrooms are safe in normal amounts, but eating excessive quantities of porcini mushrooms could exceed safe limits for toxic metals, especially for people in polluted areas.

Effect of Tricholoma matsutake Powder and Colored Rice Flour on Baking Quality and Volatile Aroma Compound of Cookie

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Researchers developed a healthier cookie recipe by adding Tricholoma matsutake mushroom powder and colored rice flour to regular cookie dough. These additions increased the nutritional value, created better flavors and aromas, and slowed down how quickly the body digests the carbohydrates in the cookies. The best recipe combined 5% mushroom powder with 20% red rice flour, creating cookies that taste good while offering potential health benefits for people concerned about blood sugar and cholesterol levels.

therapeutic action: cholesterol reduction