therapeutic action: cholesterol-lowering

Nature’s Own Pharmacy: Mushroom-Based Chemical Scaffolds and Their Therapeutic Implications

This comprehensive review explores how mushrooms can be used as natural medicines. Various mushroom species contain powerful compounds that can fight cancer, boost immunity, reduce inflammation, and treat infections. The paper details 15 important medicinal mushrooms and their therapeutic uses, showing that mushrooms are indeed a nature’s pharmacy with significant potential for treating many diseases.

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Fungal Drug Discovery for Chronic Disease: History, New Discoveries and New Approaches

This article examines how fungi have provided humanity with some of the most important medicines ever created, including penicillin, drugs that prevent organ rejection, and cholesterol-lowering statins. Many of these fungal compounds work as medicines because they target processes that are similar in both fungi and humans, helping them survive competition with other fungi while coincidentally treating human diseases. New researchers are now using modern genetic tools to discover additional fungal medicines, with several promising candidates currently being tested in clinical trials for cancer, depression, and other chronic diseases.

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Amorphophallus konjac: traditional uses, bioactive potential, and emerging health applications

Konjac is a plant used in Asian cuisine and traditional medicine for thousands of years that contains a special fiber called glucomannan. This fiber can help with weight loss, blood sugar control, and cholesterol reduction while also supporting a healthy gut and reducing inflammation. Modern research shows promising potential for using konjac to help prevent serious diseases like colorectal cancer and manage conditions like diabetes and inflammatory bowel disease.

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Exploring Therapeutic Potential of Pleurotus ostreatus and Agaricus bisporus Mushrooms against Hyperlipidemia and Oxidative Stress Using Animal Model

Oyster and white button mushrooms may help lower cholesterol and protect against heart disease. In a study using rats with high cholesterol, mushroom extracts reduced harmful cholesterol levels and improved the body’s natural defense against oxidative damage. These common, affordable mushrooms contain beneficial compounds that could be incorporated into diets as a natural way to support heart health and manage cholesterol.

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Comparative Metabolite Profiling Between Cordyceps sinensis and Other Cordyceps by Untargeted UHPLC-MS/MS

This research compares the chemical compounds found in authentic Cordyceps sinensis with four similar but different Cordyceps species to identify which ones are real. Using advanced laboratory techniques, scientists detected thousands of chemical differences between the species. They found that genuine C. sinensis contains higher levels of specific beneficial compounds like nucleosides and certain fatty acids. These findings help consumers and merchants distinguish authentic Cordyceps from counterfeit products and lower-quality substitutes.

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Phylogenetic Analysis and Nutritional Evaluation of Laetiporus Species in Korea

Researchers in Korea identified that ‘chicken of the woods’ mushrooms growing in the region are actually two specific species: Laetiporus versisporus and Laetiporus cremeiporus, not the species previously thought. These mushrooms are nutritionally impressive, containing substantial protein (9-18% depending on species) and high levels of beneficial β-glucans (15-35%), making them promising candidates as sustainable meat alternatives and functional food ingredients.

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Exploring Bioactive Compounds from Fruit and Vegetable By-Products with Potential for Food and Nutraceutical Applications

This review explores how food waste from fruit and vegetable processing can be transformed into valuable health supplements and functional foods. By-products like peels, seeds, and leaves contain powerful compounds with antioxidant and anti-inflammatory properties. Modern extraction techniques can efficiently recover these compounds in environmentally friendly ways, making it possible to create nutritious supplements while reducing food waste and supporting sustainable food production.

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Research on the Action and Mechanism of Pharmacological Components of Omphalia lapidescens

Omphalia lapidescens, a medicinal fungus used in traditional Chinese medicine, contains multiple bioactive compounds with promising health benefits. These compounds can fight parasitic infections, inhibit cancer cell growth, reduce inflammation, and provide antioxidant protection. While clinical use shows benefits especially for gastric cancer when combined with chemotherapy, more research is needed to understand how these compounds work and to improve cultivation and production methods.

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Pigment Formation by Monascus pilosus DBM 4361 in Submerged Liquid Culture

Scientists studied how to produce natural yellow, orange, and red pigments from the fungus Monascus pilosus in liquid culture. They found that the type of sugar and nitrogen used in the fermentation significantly affects pigment production. Interestingly, glucose actually reduces pigment formation through a process called carbon catabolite repression. M. pilosus offers a safer alternative to other Monascus species because it does not produce the harmful toxin citrinin, making it suitable for use in food products.

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Potential Usage of Edible Mushrooms and Their Residues to Retrieve Valuable Supplies for Industrial Applications

Edible mushrooms are not only nutritious foods but also contain valuable compounds that are being wasted during production. Scientists are discovering new ways to use mushroom waste to make useful products like natural skincare items, water purification materials, and food additives. These innovations help reduce environmental pollution while creating valuable products, supporting a more sustainable circular economy.

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