therapeutic action: cell growth inhibition

Chemical Content and Cytotoxic Activity on Various Cancer Cell Lines of Chaga (Inonotus obliquus) Growing on Betula pendula and Betula pubescens

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This study examined chaga mushroom, a traditional medicine used against cancer, grown on two types of birch trees. Researchers tested chaga extracts on 31 different cancer cell types and found they were moderately effective at inhibiting cancer cell growth, particularly against liver and thyroid cancers. The chaga from silver birch (B. pendula) worked slightly better than that from downy birch (B. pubescens) due to higher levels of a compound called inotodiol.

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Anticancer Activity of Solvent Extracts of Hexogonia glabra against Cervical Cancer Cell Lines

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Researchers tested extracts from a wild mushroom species called Hexogonia glabra against cervical cancer cells in the laboratory. The ethanolic extract was most effective, killing cancer cells by triggering apoptosis (programmed cell death) and activating genes that fight cancer. The mushroom extracts showed strong anticancer effects without harming normal cells, suggesting it could be a promising source for developing new cancer drugs.

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Staurosporine as an Antifungal Agent

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Staurosporine is a natural compound produced by soil bacteria that can kill fungi. Scientists originally discovered it in 1977 and found it works by blocking proteins called kinases that fungi need to survive. Recent research shows it could be useful against drug-resistant fungal infections, especially when combined with other antifungal medicines. However, it needs to be modified to make it safer for human use.

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Encapsulation of progesterone in reishi mushroom composite for optimized hormone replacement and targeted anticancer therapy

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Researchers created a new treatment by combining progesterone (a hormone) with reishi mushroom powder to make it work better in the body. The mushroom acts like a protective wrapper that slowly releases the hormone, making it more effective for treating menopausal symptoms and fighting breast cancer cells. The combination also fights harmful bacteria and fungi while remaining stable during storage. This approach combines traditional medicine with modern pharmaceutical science.

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Physicochemical Characteristics of Chitosan Extracted from Pleurotus ostreatus and Its Anticancer Activity Against the MDA-MB-231 Breast Cancer Cell Line

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Researchers extracted a compound called chitosan from oyster mushrooms (Pleurotus ostreatus) and tested its ability to fight breast cancer cells. The chitosan successfully killed cancer cells by triggering apoptosis, a natural cell death process, while showing promise as a safer alternative to conventional chemotherapy. The study demonstrates that mushroom-derived compounds could have significant therapeutic potential for cancer treatment with fewer side effects than traditional drugs.

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