therapeutic action: blood pressure reduction

Bioactive Metabolites from the Fruiting Body and Mycelia of Newly-Isolated Oyster Mushroom and Their Effect on Smooth Muscle Contractile Activity

Researchers isolated a new oyster mushroom strain and studied how it affects digestive system health. They compared the fruiting body and mycelium (root-like structure) and found that water extracts of the fruiting body were rich in beneficial compounds like β-glucans and antioxidants. When tested on stomach muscle tissue, these extracts caused muscle contractions in a dose-dependent manner, suggesting potential benefits for digestive function. This discovery could lead to new natural supplements supporting gut health.

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Enhancing Pearl oyster mushroom (Pleurotus ostreatus) performance by evaluating the influence of potassium humate and wheat straw on yield and biochemical attributes

This study examined how adding potassium humate (a natural organic compound) to wheat straw substrate affects the growth and quality of oyster mushrooms. Researchers tested seven different amounts of potassium humate over two growing seasons and found that a moderate amount (0.5 g per 500 g straw) produced the best results, increasing both mushroom yield and nutritional value including vitamin C and beneficial sugars. Interestingly, using more potassium humate was not better, showing that balanced application is more effective than maximum supplementation for optimal mushroom production.

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Whole-Genome Sequencing and Comparative Genomics Analysis of the Wild Edible Mushroom (Gomphus purpuraceus) Provide Insights into Its Potential Food Application and Artificial Domestication

Scientists sequenced the complete genetic code of Gomphus purpuraceus, a wild mushroom eaten in southwest China for hundreds of years. By comparing its genes to other edible mushrooms, researchers discovered it likely forms beneficial partnerships with trees and can break down some plant material. The study shows this mushroom can efficiently use simple sugars like sucrose and maltose for growth, which could help farmers grow it commercially while preserving this rare species.

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Optimisation and Characterisation of Novel Angiotensin-Converting Enzyme Inhibitory Peptides Prepared by Double Enzymatic Hydrolysis from Agaricus bisporus Scraps

Scientists discovered three new peptides in common button mushroom scraps that can lower blood pressure by blocking an enzyme called ACE. Using special enzymes to break down mushroom proteins and then purifying the result, they created peptides with strong blood pressure-lowering activity that survive stomach digestion well. This finding turns mushroom waste into a valuable source for making natural blood pressure medications that are safer than synthetic alternatives.

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Impact of Air-Drying Temperature on Antioxidant Properties and ACE-Inhibiting Activity of Fungal Fermented Lentil Flour

Researchers fermented lentils with oyster mushrooms to create nutritious flour with health benefits. Two lentil varieties responded differently to fermentation, with one showing four times more mushroom growth and nearly complete removal of phytic acid (an antinutrient). The fermented flour was dried at different temperatures and tested for antioxidant and blood pressure-lowering properties. Results show the fermented flours have promising cardiovascular benefits and could be used as healthy food ingredients.

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Edible Mushrooms and Beta-Glucans: Impact on Human Health

Mushrooms contain compounds called β-glucans that can help boost your immune system and reduce inflammation. These compounds show promise in cancer treatment when combined with conventional therapies and may help fight infections. While mushrooms have long been used in traditional medicine, modern research is confirming their health benefits and understanding how they work in the body.

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Combined effect of olive pruning residues and spent coffee grounds on Pleurotus ostreatus production, composition, and nutritional value

This study examined growing oyster mushrooms on different substrate mixtures combining wheat straw with recycled coffee grounds and olive plant waste. The researchers found that mushrooms grown on substrates with lower amounts of these waste materials produced comparable yields to standard straw while offering better nutritional profiles, including higher protein and lower fat content. The findings suggest that using these recycled agricultural wastes could benefit mushroom farming in regions where wheat straw is difficult to obtain, though lead contamination from coffee grounds was a concern requiring better cleaning procedures.

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Promoting rational herb-drug use through pharmacy-led advice and home visits in NCD patients

This study showed that when pharmacists visited NCD patients at home and provided education about the risks of combining herbal products with prescribed medications, patients significantly improved their knowledge and safe usage behaviors. The intervention successfully reduced the number of patients at risk of harmful herb-drug interactions from 37.5% to 25%. The findings suggest that simple home-based pharmacist counseling can be an effective way to help chronic disease patients safely use both herbs and medications together.

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