therapeutic action: blood clot dissolution

Purification and Biochemical Characterization of a Novel Fibrinolytic Enzyme from Culture Supernatant of Coprinus comatus

Scientists discovered and purified a powerful enzyme from the medicinal mushroom Coprinus comatus that can dissolve blood clots and prevent dangerous blood vessel blockages. This enzyme works in two ways: it can directly break down clots and also activate the body’s natural clot-dissolving systems. The enzyme is much smaller and safer than current blood-thinning medications, making it a promising natural alternative for treating heart disease and stroke.

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Diverse origins of fibrinolytic enzymes: A comprehensive review

Blood clots can cause heart attacks and strokes, which are major causes of death worldwide. Currently used clot-dissolving drugs have significant drawbacks including short effectiveness periods and side effects. This review examines how fibrinolytic enzymes—naturally occurring proteins that dissolve blood clots—can be obtained from various sources, especially fermented foods like Japanese natto. These enzymes show promise as safer, cheaper alternatives that could be produced in large quantities for treating cardiovascular diseases.

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