therapeutic action: Autophagy induction

The Anticancer Potential of Edible Mushrooms: A Review of Selected Species from Roztocze, Poland

This review examines edible mushrooms found in Poland’s Roztocze region for their potential to fight cancer. These mushrooms contain natural compounds like polysaccharides and proteins that can kill cancer cells in laboratory studies through various mechanisms, including triggering cell death and boosting immune function. While promising, these findings from laboratory and animal studies need further development before becoming clinical treatments.

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A tale for two roles: Root-secreted methyl ferulate inhibits P. nicotianae and enriches the rhizosphere Bacillus against black shank disease in tobacco

Tobacco plants release a natural chemical called methyl ferulate from their roots that has a powerful two-pronged defense against a devastating soil disease called black shank. First, the methyl ferulate directly kills the fungus by disrupting its energy production. Second, it attracts beneficial bacteria called Bacillus to the soil around the roots, which further fight the disease. Scientists found they could boost this defense by engineering a tobacco gene that produces more methyl ferulate, making plants much more resistant to infection. This discovery offers farmers an affordable, natural way to control soil diseases without synthetic chemicals.

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Chaga mushroom triterpenoids as adjuncts to minimally invasive cancer therapies: A review

Chaga mushroom, a fungus that grows on birch trees, contains special compounds called triterpenoids that can kill cancer cells in laboratory tests. Some of these compounds, particularly inotodiol and betulinic acid, show anti-cancer activity similar to or better than conventional chemotherapy drugs. While promising, researchers need to improve how these compounds are absorbed in the body and test them more thoroughly in animals and humans before they can be used clinically.

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Can Ganoderma Triterpenoids Exert Immunogenic Cell Death in Human Cancer Cells? A Systematic Review and Protein Network Analysis

This review examines whether compounds from medicinal mushrooms called Ganoderma can help the body’s immune system fight cancer more effectively. Researchers analyzed 69 scientific studies and found that Ganoderma compounds cause cancer cells to die and trigger immune-activating signals. While these results are promising, more experiments are needed to prove whether these mushroom compounds actually activate the specific immune pathways required for long-term cancer control.

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Three-phase extraction of polysaccharide from Stropharia rugosoannulata: Process optimization, structural characterization and bioactivities

Researchers developed an efficient new method called three-phase extraction to isolate beneficial compounds called polysaccharides from wine cap mushrooms (Stropharia rugosoannulata). These polysaccharides showed strong antioxidant properties and boosted immune cell activity in laboratory tests by triggering specific cellular pathways. The findings suggest these mushroom extracts could become useful ingredients in functional foods or medicines to support immune health.

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