therapeutic action: autophagy activation

Impact of Hericium erinaceus and Ganoderma lucidum metabolites on AhR activation in neuronal HT-22 cells

mycolabadmin

This study examined how two medicinal mushrooms, lion’s mane and Reishi, affect nerve cells in the brain. The researchers found that metabolites from these mushrooms don’t harm brain cells and actually boost protective proteins that support cell health and survival. The mushrooms appear to work through a cellular receptor called AhR, which helps facilitate communication between the gut and the brain. These findings suggest that these mushrooms may help support brain function and protect against neurological problems.

Read More »

The Potential of Naturally Derived Compounds for Treating Chronic Kidney Disease: A Review of Autophagy and Cellular Senescence

mycolabadmin

This review explores how natural products from traditional Chinese medicine may help treat chronic kidney disease by targeting two key aging processes: autophagy (cellular self-cleaning) and cellular senescence (cellular aging). Common natural compounds like curcumin, green tea extract, and Astragalus have shown promise in protecting kidney function and reducing harmful inflammation. While these natural treatments show potential as complementary therapies alongside mainstream medicines, more clinical research is needed to confirm their effectiveness and determine optimal dosages.

Read More »

Terpinen-4-ol triggers autophagy activation and metacaspase-dependent apoptosis against Botrytis cinerea

mycolabadmin

Terpinen-4-ol, a natural compound from tea tree oil, effectively kills gray mold fungus that spoils fruits and vegetables after harvest. The compound works by damaging fungal cell membranes, creating harmful reactive molecules inside fungal cells, and triggering the fungal cells’ self-destruction pathways. When tested on tomatoes and strawberries, terpinen-4-ol successfully reduced mold growth and disease spread, suggesting it could be a safe, eco-friendly alternative to chemical fungicides for protecting fresh produce.

Read More »

The Biological Activity of Ganoderma lucidum on Neurodegenerative Diseases: The Interplay between Different Active Compounds and the Pathological Hallmarks

mycolabadmin

Reishi mushroom, used in traditional Asian medicine for centuries, contains over 400 bioactive compounds that show promise in protecting the brain from degenerative diseases like Alzheimer’s and Parkinson’s. The mushroom’s components work through multiple pathways to reduce inflammation, fight oxidative stress, and protect neurons from damage. While laboratory and animal studies show encouraging results, human clinical trials are needed to confirm its effectiveness as a treatment.

Read More »

The mycelium of the Trametes versicolor synn. Coriolus versicolor (Turkey tail mushroom) exhibit anti-melanoma activity in vitro

mycolabadmin

Turkey tail mushrooms, used in traditional Chinese medicine for thousands of years, show promise in fighting melanoma skin cancer. Scientists tested mushroom extracts on melanoma cells in the laboratory and found they kill cancer cells through multiple mechanisms, including triggering programmed cell death and activating the immune system. The mushroom extract also reduced cancer cell migration and showed potential to work better when combined with standard chemotherapy drugs like paclitaxel. These findings suggest turkey tail could be a valuable addition to melanoma treatment strategies.

Read More »
Scroll to Top