Apoptosis induction – Page 6

Potential of traditional Chinese medicine in gastrointestinal disorders: Hericium erinaceus in chronic atrophic gastritis

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Lion’s Mane mushroom (Hericium erinaceus) shows promise for treating chronic stomach inflammation and preventing gastric cancer. Studies indicate it can reduce stomach pain, improve endoscopic findings, and fight harmful bacteria like H. pylori. Its active compounds work by reducing inflammation, oxidative stress, and promoting cancer cell death, offering a natural complement to conventional treatments.

Taxonomic characterization and cytotoxic potential of Vietnamese Ganoderma ellipsoideum against human breast cancer MCF-7 cells

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Scientists discovered a mushroom species called Ganoderma ellipsoideum in Vietnam that shows promise in fighting breast cancer. When tested on cancer cells in the laboratory, extracts from this mushroom killed cancer cells effectively. Computer modeling showed that compounds from this mushroom fit perfectly into and block proteins that help cancer cells grow and spread. This discovery suggests the mushroom could be a natural source for developing new cancer drugs.

Microbial-Based Green Synthesis of Silver Nanoparticles: A Comparative Review of Bacteria- and Fungi-Mediated Approaches

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Scientists have developed environmentally friendly ways to create tiny silver particles using bacteria and fungi instead of harsh chemicals. These silver nanoparticles can fight bacteria, help treat cancer, clean contaminated water, and improve food packaging. The review shows that bacteria produce particles quickly but fungi are better for large-scale production and create more stable particles.

Harnessing pycnidia-forming fungi for eco-friendly nanoparticle production, applications, and limitations

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Scientists are using special fungi called pycnidial fungi to create tiny nanoparticles that could revolutionize medicine and environmental cleanup. These fungi naturally produce chemicals that can turn metal into useful nanoparticles without the toxic processes used in factories. The resulting nanoparticles show promise in fighting bacteria, cancer cells, and cleaning polluted water, offering a safer and more eco-friendly alternative to traditional methods.

Microbial-Based Green Synthesis of Silver Nanoparticles: A Comparative Review of Bacteria- and Fungi-Mediated Approaches

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Scientists are developing environmentally friendly ways to make silver nanoparticles using bacteria and fungi instead of harsh chemicals. These tiny particles show promise in fighting infections, treating cancer, cleaning water, and protecting crops. The review compares how bacteria and fungi each produce these particles and explains how different conditions affect their properties and effectiveness.

Eco-friendly biosynthesis of silver nanoparticles using marine-derived Fusarium equiseti: optimization, characterization, and evaluation of antimicrobial, antioxidant, and cytotoxic activities

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Scientists used a marine fungus called Fusarium equiseti to create tiny silver particles called nanoparticles in an environmentally-friendly way. These particles showed strong abilities to kill harmful bacteria and fungi, protect cells from damage caused by free radicals, and fight breast cancer cells in laboratory tests. This green synthesis method offers a safer, non-toxic alternative to traditional chemical manufacturing while producing stable, multi-functional nanoparticles.

Study on Optimization of Liquid Fermentation Medium and Antitumor Activity of the Mycelium on Phyllopora lonicerae

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Scientists optimized how to grow Phylloporia lonicerae fungus in the lab, increasing its production by 142% while cutting growth time by two-thirds. They discovered that certain compounds extracted from this fungus, particularly from a petroleum ether extract, can kill cancer cells and trigger apoptosis. The petroleum ether extract was more effective than the standard cancer drug 5-fluorouracil, especially against esophageal cancer cells, suggesting this fungus could be developed into a natural anti-cancer treatment.

Staurosporine as an Antifungal Agent

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Staurosporine is a natural compound produced by soil bacteria that can kill fungi. Scientists originally discovered it in 1977 and found it works by blocking proteins called kinases that fungi need to survive. Recent research shows it could be useful against drug-resistant fungal infections, especially when combined with other antifungal medicines. However, it needs to be modified to make it safer for human use.

Interplay of precision therapeutics and MD study: Calocybe indica’s potentials against cervical cancer and its interaction with VEGF via octadecanoic acid

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Researchers discovered that an extract from the Calocybe indica mushroom effectively kills cervical cancer cells while leaving healthy immune cells unharmed. Using computer simulations, they identified that a compound in this mushroom called octadecanoic acid strongly binds to and blocks VEGF, a protein that helps cancer cells grow and spread. The extract reduced cancer cell movement by 50% and prevented cancer cells from forming colonies, suggesting this mushroom could become a new treatment option for cervical cancer.

Synergistic Effects of Cold Atmospheric Multiple Plasma Jet and Amphotericin B on Leishmania major: An In-Vitro Study

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Researchers tested a new cold plasma technology combined with an existing anti-parasite drug (amphotericin B) against Leishmania parasites that cause skin infections. The cold plasma, which contains reactive chemicals, killed the parasites by triggering their programmed cell death (apoptosis) while causing minimal harm to human immune cells. When combined with the medication, the treatment was even more effective, potentially allowing lower drug doses with fewer side effects.

therapeutic action: Apoptosis induction