therapeutic action: antiviral

Effects of ultrasound-assisted extraction and transglutaminase treatment on the physicochemical properties of protein from Stropharia rugosoannulata

Researchers developed improved methods to extract and modify protein from Stropharia rugosoannulata mushrooms to make them better for use in plant-based meat products. Using ultrasound waves and an enzyme called transglutaminase, they were able to increase the protein yield and improve how well the protein can hold water and oil. These modifications enhanced the mushroom protein’s ability to work as a meat substitute in food products.

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Pan-genomic characterization and structural variant analysis reveal insights into spore development and species diversity in Ganoderma

Researchers completed the first comprehensive genome study of 15 Ganoderma (Lingzhi/Reishi) varieties, including five new Chinese strains. They discovered that specific genetic changes in the MSH4 gene dramatically increase spore production in one superior strain. These findings help explain why different Ganoderma varieties have different medicinal properties and can guide breeding of better medicinal mushroom varieties.

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Enhancement and Mechanism of Ergosterol Biosynthesis in Termite Ball Fungus Athelia termitophila by Methyl Jasmonate

Scientists studied how to increase ergosterol production in termite ball fungus, a medicinal fungus used in traditional medicine. By adding methyl jasmonate, a natural signaling molecule, they more than doubled ergosterol content. Ergosterol is used to make vitamin D2 and certain medications for inflammation and cancer. The study identified which genes need to be activated for better ergosterol production, providing insights for creating more effective medical products from fungi.

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Proteins from Edible Mushrooms: Nutritional Role and Contribution to Well-Being

Mushrooms are highly nutritious foods containing proteins as complete and high-quality as meat, with unique compounds that boost immunity, fight infections, and may help prevent diseases like cancer and diabetes. Different types of mushroom proteins have specific health benefits, from strengthening immune systems to lowering blood pressure and fighting viruses. Scientists are finding new ways to grow mushrooms and extract their proteins for use in sports nutrition, medicines, and fortified foods, making them increasingly valuable for human health and sustainability.

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The Benefits and Applications of Lactobacillus plantarum in Food and Health: A Narrative Review

Lactobacillus plantarum is a beneficial bacterium commonly found in fermented foods like yogurt and cheese that acts as a natural probiotic. It can help preserve food, improve flavor, and boost health by supporting digestion, strengthening immunity, and reducing inflammation. Research shows it may help with weight management, blood sugar control, and mental health, making it valuable for both the food industry and medical applications.

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The rise of Stropharia rugosoannulata industry in China: current state and prospects

The wine-cap mushroom (Stropharia rugosoannulata) is becoming a major agricultural industry in China with over 494,000 tons produced annually. This large, meaty mushroom is rich in proteins, minerals, and healing compounds that may help fight diabetes, obesity, and heart disease. It grows easily on agricultural waste materials, making it an environmentally friendly crop that’s being used to help rural communities and reduce farming pollution.

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Bibliometric, taxonomic, and medicinal perspectives of Ganoderma neo-japonicum Imazeki: A mini review

Ganoderma neo-japonicum, known as purple Lingzhi, is a mushroom traditionally used by indigenous communities in Malaysia and other Asian countries to treat various health conditions. This review examines 36 scientific studies published between 1991 and 2021, showing that the mushroom contains special compounds that can fight cancer cells, lower blood sugar, reduce inflammation, and boost immunity. While laboratory studies show promising results, the mushroom still needs more clinical testing in humans before it can be widely used as a medicine.

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The First Whole Genome Sequence and Methylation Profile of Gerronema lapidescens QL01

Researchers sequenced the complete genome of Lei Wan (Gerronema lapidescens), a medicinal mushroom used in Chinese traditional medicine for treating parasites and digestive issues. The study reveals the mushroom’s genetic makeup, including 15,847 genes and over 3 million methylation marks that may control gene expression. They identified 67 gene clusters that could produce medicinal compounds and 521 enzymes for breaking down organic matter. This genetic blueprint will help scientists understand how to cultivate this threatened species sustainably and develop its health benefits.

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Comparative Multi-Omics Analysis and Antitumor Activity of Phylloporia crataegi and Phylloporia fontanesiae

Two species of medicinal fungi were studied to understand why one was better at fighting cancer cells. Researchers analyzed the chemicals, genes, and proteins in both fungi and found that Phylloporia crataegi had much higher levels of cancer-fighting compounds and activated special cellular defense pathways that harm cancer cells. This research shows that medicinal fungi could be promising sources for developing new cancer treatments.

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The First Whole Genome Sequence and Methylation Profile of Gerronema lapidescens QL01

Scientists have sequenced the complete genetic code of Lei Wan (Gerronema lapidescens), a medicinal mushroom used in traditional Chinese medicine for treating parasitic infections and digestive problems. The research revealed how this mushroom produces beneficial compounds and how its genes are regulated through a process called methylation. This information could help develop better ways to cultivate this increasingly rare mushroom sustainably rather than harvesting it from the wild, making it available for future medical research and treatment.

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