antiviral – Page 6

Research on the Action and Mechanism of Pharmacological Components of Omphalia lapidescens

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Omphalia lapidescens, a medicinal fungus used in traditional Chinese medicine, contains multiple bioactive compounds with promising health benefits. These compounds can fight parasitic infections, inhibit cancer cell growth, reduce inflammation, and provide antioxidant protection. While clinical use shows benefits especially for gastric cancer when combined with chemotherapy, more research is needed to understand how these compounds work and to improve cultivation and production methods.

Therapeutic Potential of Bioactive Compounds in Edible Mushroom-Derived Extracellular Vesicles: Isolation and Characterization of EVs from Pleurotus eryngii

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Scientists have isolated and studied tiny capsule-like particles called extracellular vesicles from the oyster mushroom Pleurotus eryngii. These vesicles, which are naturally produced by the mushroom, contain beneficial compounds like antioxidants that help protect cells from damage. The researchers found that vesicles from mushroom mycelium (the root-like part) were of higher quality and had stronger antioxidant effects than those from the fruiting body. These findings suggest that mushroom-derived vesicles could potentially be developed into health supplements or therapeutic treatments.

Impact of Interactions Between Zn(II) and Selenites in an Aquatic Environment on the Accumulation of Se and Zn in a Fungal Cell

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Researchers studied how Shiitake mushrooms accumulate selenium and zinc from growth media, finding that these two elements form chemical complexes that interfere with absorption. When both elements are present together in the culture medium, they bind to each other instead of being taken up by the mushroom cells, reducing the final content of both nutrients. Understanding this interaction is important for developing enhanced mushroom-based dietary supplements containing both selenium and zinc.

The First Whole Genome Sequence and Methylation Profile of Gerronema lapidescens QL01

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Scientists have sequenced the complete genome of Lei Wan (Gerronema lapidescens), a medicinal mushroom used in traditional Chinese medicine for treating parasitic infections and digestive problems. The research reveals the mushroom’s genetic blueprint, including genes responsible for producing beneficial compounds and adapting to rocky mountain environments. This foundational work aims to enable sustainable cultivation of this rare fungus and development of new medicinal treatments, addressing current conservation threats from over-harvesting.

Effects of Natural Polysaccharides on the Gut Microbiota Related to Human Metabolic Health

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Natural plant and organism sugars called polysaccharides can improve your gut health by feeding beneficial bacteria and strengthening your intestinal barrier. These compounds help prevent diseases like obesity, diabetes, and inflammatory bowel disease by changing the types of bacteria in your gut and producing helpful substances. Polysaccharides come from common foods like mushrooms, seaweed, berries, and vegetables, making them potential natural treatments for various health conditions.

Traditional uses, chemical components and pharmacological activities of the genus Ganoderma P. Karst.: a review

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Ganoderma, a medicinal fungus used in traditional medicine for over 2000 years, contains many beneficial compounds including triterpenes and polysaccharides. Scientific research has confirmed its effectiveness in treating various conditions including cancer, diabetes, infections, and inflammation. The fungus works by boosting the immune system, reducing oxidative stress, and directly inhibiting disease-causing organisms. Modern cultivation methods have made Ganoderma products widely available as supplements and medicines worldwide.

Bioactive Steroids Bearing Oxirane Ring

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This research reviews special types of steroids that contain oxirane rings, which are highly reactive chemical structures found in marine organisms, fungi, and plants. These compounds have shown promise in treating various diseases including cancer, inflammation, and high cholesterol. Scientists used computer software to predict and analyze the biological activities of over 150 different epoxy steroids, categorizing them by the position of their oxirane ring. The findings suggest these natural compounds could be valuable for developing new medicines and understanding how chemicals interact with our bodies.

New bioactive secondary metabolites from fungi: 2024

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Scientists discovered 907 new compounds from fungi in 2024, with most being terpenoids and polyketides that show promise as medicines. These fungal compounds demonstrate strong activity against bacteria, fungi, and inflammation, with some showing potential against cancer and diabetes. The research uses advanced techniques like genome mining and metabolomics to find these compounds more efficiently. This accelerating discovery rate suggests fungi could be a major source for developing new drugs to treat various diseases.

Morphological and Phylogenetic Characterization of Endophytic Fungi Isolated from Brown Algae (Phaeophyceae) in Korea

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Researchers in Korea isolated and identified three types of fungi never before recorded in the country that live inside brown seaweed. These fungi were found in Sargassum species collected from Korean coastal areas and were identified using DNA analysis and microscopy. The discovery reveals that Korean seaweed harbors diverse fungal communities that may produce useful compounds for medicine and agriculture, highlighting the unexplored potential of marine ecosystems.

Genomic insights into the ecological versatility of Tetracladium spp

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Researchers sequenced the genomes of two fungal species called Tetracladium that live in different environments – one found in plant roots and one from freshwater. These fungi have special enzymes that allow them to break down plant cell walls and materials, enabling them to survive in multiple habitats. The study revealed these fungi can also produce compounds with potential medical properties like antifungal and antibacterial effects.

therapeutic action: antiviral