therapeutic action: antiviral activity

Pigment production by a newly isolated strain Pycnoporus sanguineus SYBC-L7 in solid-state fermentation

Researchers isolated a fungal strain that produces bright orange natural pigments through fermentation on wood chips and other agricultural waste. By optimizing growing conditions such as pH and moisture, they achieved high pigment yields with antibacterial properties. The pigments identified in this study showed effectiveness against harmful bacteria and could replace synthetic dyes in food, cosmetics, and textile products.

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Bibliometric analysis of traditional Chinese medicine for viral infections through immune modulation (2015–2025)

This research analyzed over 3,300 scientific papers published between 2015-2025 to understand how traditional Chinese medicine helps fight viral infections by boosting the immune system. The study found that research on this topic has grown significantly, especially during disease outbreaks like COVID-19, with China leading in research publications. Key findings show that traditional Chinese herbal compounds work through multiple mechanisms including directly fighting viruses, reducing excessive inflammation, and enhancing vaccine effectiveness. The research points toward promising future applications of traditional Chinese medicine when combined with modern medical approaches.

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Mitochondrial genome characterization, evolution and intron dynamics of the entomopathogenic genus Cordyceps

This research examined the genetic instruction manuals (mitochondrial DNA) of seven different Cordyceps fungal species. Scientists found that these fungi have varying amounts of genetic material, primarily due to differences in introns—sections that can be inserted or removed from genes. By comparing their genomes, researchers clarified how different Cordyceps species are related to each other evolutionarily, providing better tools for identifying and classifying these medically valuable fungi.

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Koumiss (Fermented Mare’s Milk) as a Functional Food: Bioactive Proteins, Peptides, and Future Perspectives

Koumiss is a fermented mare’s milk beverage consumed for centuries in Central Asia that offers unique health benefits. Unlike cow’s milk, mare’s milk is easier to digest, contains natural antimicrobial proteins, and when fermented develops thousands of bioactive peptides and beneficial bacteria. These compounds may help with cardiovascular health, gut function, and immune support, making koumiss a promising functional food for modern nutrition.

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Global species diversity and distribution of the psychedelic fungal genus Panaeolus

This study is a comprehensive catalog of 77 Panaeolus mushroom species worldwide, of which 20 are known to be hallucinogenic and contain psilocybin. Researchers found that these mushrooms are most commonly documented in Asia, South America, and Europe, but many regions have little to no research data. The review highlights significant gaps in our knowledge about where these species exist and which ones truly contain psychoactive compounds, information that is crucial as these fungi become legal in more countries for medical use.

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Advanced Fungal Biotechnologies in Accomplishing Sustainable Development Goals (SDGs): What Do We Know and What Comes Next?

Fungi are remarkable organisms with tremendous untapped potential for solving global challenges. They can be engineered to produce life-saving medicines like antibiotics and cholesterol-lowering drugs, create nutritious food alternatives, clean up polluted environments, and help fight climate change. As we transition to more sustainable living practices, fungi represent a natural solution that has been used for centuries but is only now being fully appreciated through modern biotechnology.

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Cultivation and mycelium production from spore suspensions of desert truffles: prospective use as inoculum for host plants in arid zones

Desert truffles are valuable edible fungi that grow in arid regions and have health benefits. This research successfully grew two desert truffle species (Terfezia boudieri and Tirmania nivea) in laboratory conditions using standard culture media. The study found that potato dextrose agar was the best medium for rapid growth, while both media supported good mycelial development. This breakthrough could enable large-scale production of truffle inoculum for reforestation programs in Morocco’s degraded desert areas.

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Screening and identifying natural products with SARS-CoV-2 infection inhibitory activity from medicinal fungi

Researchers screened 167 extracts from 36 medicinal fungi to find natural compounds that could fight COVID-19. They discovered that certain fungi, particularly Inonotus obliquus and Pholiota adiposa, contain polysaccharides that effectively block the virus from infecting cells. These natural compounds showed promise as potential safe alternatives for developing new COVID-19 treatments and may have applications against other viral diseases.

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Exploring the health benefits of Ganoderma: antimicrobial properties and mechanisms of action

Ganoderma is a medicinal mushroom that has been used in traditional medicine for thousands of years and is now being studied for its ability to fight infections. The mushroom contains special compounds like polysaccharides and triterpenoids that can kill harmful bacteria and fungi in multiple ways—by breaking down their cell walls, stopping them from reproducing, and boosting your immune system. Scientists have found that Ganoderma works against many dangerous bacteria including antibiotic-resistant strains, and it may offer a natural alternative to conventional antibiotics as antibiotic resistance becomes a major global health problem.

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Enhancement of Perylenequinonoid Compounds Production from Strain of Pseudoshiraia conidialis by UV-Induced Mutagenesis

Researchers used UV light to mutate fungal strains that naturally produce powerful medicinal compounds called perylenequinones. These compounds show promise for treating cancer and viral infections through photodynamic therapy. Through careful mutagenesis and screening, they developed a superior fungal strain that produces over 2100 mg/L of these valuable compounds, far exceeding previous methods. The breakthrough highlights that focusing on multiple beneficial compounds rather than just one can lead to better commercial applications.

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