antitumor – Page 2

Therapeutic Potential of Bioactive Compounds in Edible Mushroom-Derived Extracellular Vesicles: Isolation and Characterization of EVs from Pleurotus eryngii

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Researchers isolated tiny particles called extracellular vesicles (EVs) from a medicinal mushroom called king oyster mushroom (Pleurotus eryngii). These EVs act like natural delivery packages containing beneficial compounds like antioxidants and anti-inflammatory molecules. The study found that EVs from mushroom mycelium (the root-like part) were purer and more potent than those from the mushroom cap, with strong abilities to neutralize harmful free radicals in the body.

Ultrasound-assisted extraction of neuroprotective antioxidants from Ganoderma lucidum

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This research studied how to best extract healing compounds from the reishi mushroom (Ganoderma lucidum), an important traditional Chinese medicine. Using advanced extraction techniques and computer modeling, scientists identified optimal conditions that doubled the amount of beneficial antioxidants obtained compared to conventional methods. They then tested these extracts on nerve cells in the laboratory, demonstrating that the extracts effectively protected cells from oxidative damage and injury.

Prebiotic and Functional Fibers from Micro- and Macroalgae: Gut Microbiota Modulation, Health Benefits, and Food Applications

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Seaweed and other algae contain special fibers called polysaccharides that act like fertilizer for beneficial bacteria in your gut. When these good bacteria ferment these algal fibers, they produce substances called short-chain fatty acids that support digestive health, boost immunity, and help control blood sugar and weight. These algae-based fibers are sustainable alternatives to synthetic prebiotics and can be added to foods and supplements.

Establishment of a genetic transformation system for cordycipitoid fungus Cordyceps chanhua

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Scientists have successfully developed a method to genetically modify Cordyceps chanhua, an important medicinal mushroom used in traditional Chinese medicine for over 1,600 years. By optimizing how they prepare fungal cells and introduce foreign genes, they created a reliable genetic transformation system that can be used to study which genes produce beneficial compounds in this mushroom. This breakthrough will help researchers understand and potentially enhance the medicinal properties of C. chanhua.

Substrate composition effect on the nutritional quality of Pleurotus ostreatus (MK751847) fruiting body

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Researchers studied how different growing materials affect the nutritional value of oyster mushrooms. They found that mushrooms grown on palm oil waste mixed with wheat or rice bran had better nutritional quality than those grown on single materials. The best mushrooms for protein came from materials containing wheat bran, while fermented materials produced the most vitamins. This research shows how agricultural waste can be recycled into nutritious food.

Biphasic Fermentation of Trapa bispinosa Shells by Ganoderma sinense and Characterization of Its Polysaccharides and Alcoholic Extract and Analysis of Their Bioactivity

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This study investigated fermenting water chestnut shells with a medicinal mushroom called Ganoderma sinense to create a more potent health product. Under optimal fermentation conditions, the resulting material showed significantly improved immune-boosting and antioxidant properties when tested in laboratory cells. The fermentation process changed the structure of polysaccharides and increased beneficial compounds, potentially transforming agricultural waste into a valuable functional food or supplement.

The Emerging Role of Oyster Mushrooms as a Functional Food for Complementary Cancer Therapy

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Oyster mushrooms contain special compounds that may help fight cancer and boost the immune system. These mushrooms have antioxidants and other natural chemicals that can slow cancer cell growth and trigger cancer cells to die. When combined with standard cancer treatments, oyster mushroom supplements might improve quality of life and reduce side effects. More research is needed, but oyster mushrooms show promise as an affordable, natural addition to cancer treatment plans.

Optimization of Protoplast Preparation and Establishment of PEG-Mediated Genetic Transformation Method in Cordyceps cicadae

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Scientists successfully developed a method to genetically modify Cordyceps cicadae, a valuable medicinal fungus used in traditional Chinese medicine. By optimizing how to remove the fungus’s protective cell wall and introducing new genes using a technique called PEG-mediated transformation, researchers created a stable system for genetic manipulation. This breakthrough opens the door for improving medicinal compounds in this fungus and advancing its use in treating various health conditions.

Extraction, Characterization, Biological Properties, and X-Ray Fluorescence Analysis of Functional Polysaccharides Derived from Limnospira platensis

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Spirulina (Limnospira platensis) is a nutrient-dense microalga that contains beneficial polysaccharides with multiple health benefits. Researchers extracted and analyzed these polysaccharides, finding they have strong antioxidant properties and can help regulate blood sugar levels by inhibiting α-glucosidase enzymes. These compounds also support beneficial gut bacteria growth, making spirulina a promising natural ingredient for functional foods and health supplements.

Recent developments of tools for genome and metabolome studies in basidiomycete fungi and their application to natural product research

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Mushrooms and related fungi in the basidiomycete group produce many useful medicines and agricultural chemicals. Scientists have traditionally struggled to study these fungi because they grow slowly and have complex genomes. Recent technological breakthroughs—including faster DNA sequencing and gene-editing tools—are now making it much easier to discover and understand the helpful compounds these fungi produce, potentially leading to new medicines.

therapeutic action: antitumor