antitumor activity – Page 3

A Model of the Current Geographic Distribution and Predictions of Future Range Shifts of Lentinula edodes in China Under Multiple Climate Change Scenarios

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Shiitake mushrooms (Lentinula edodes) are popular edible mushrooms found throughout China with high nutritional value including immune-boosting compounds. This study used computer modeling to map where these mushrooms currently grow and predict where they might be found as climate change continues. The research found that shiitake mushrooms will likely lose significant habitat area and shift northward and westward as temperatures rise and precipitation patterns change, suggesting urgent conservation measures are needed to protect wild populations.

Isolation and Structural Characterization of Melanins from Red and Yellow Varieties of Stropharia rugosoannulata

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Researchers studied the pigments that give mushrooms their colors, specifically looking at red and yellow varieties of wine cap mushrooms. They found that these colors come from melanin, the same pigment found in human skin. The study revealed that the red variety has more of certain melanin types than the yellow variety, which explains why they look different. These pigments could have health benefits because melanins are known to have antioxidant and anti-tumor properties.

Revealing the metabolic potential and environmental adaptation of nematophagous fungus, Purpureocillium lilacinum, derived from hadal sediment

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Scientists discovered a special fungus living in the deepest part of the ocean (Mariana Trench) that can survive extreme pressure and produce compounds with disease-fighting properties. This fungus, Purpureocillium lilacinum, showed promise against bacteria, cancer cells, and parasitic worms. The research revealed how this fungus adapts to survive in one of Earth’s most extreme environments, potentially opening new sources for developing medicines and biological pest control.

Unlocking Reishi’s secrets: nutritional and medicinal traits of Ganoderma lucidum isolated from tree bark in Egypt

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Reishi mushrooms (Ganoderma lucidum) from Egypt show promise as natural medicine. Researchers tested extracts and found they can fight bacteria, viruses, and cancer cells in laboratory tests. The mushrooms are rich in beneficial compounds like vitamins and antioxidants. While the extract was not as strong as conventional drugs, it showed good safety profiles and potential for development into new medicines.

The First Report on Agarwood Formation of Aquilaria sinensis (Lour.) Spreng Induced by Fusarium equiseti

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Researchers successfully induced agarwood (a valuable medicinal resin) formation in Chinese agar trees using a fungus called Fusarium equiseti. Through careful analysis, they found the fungus triggered production of beneficial compounds like agarotetrol and aromatic sesquiterpenes within 12 months, matching quality standards for medicinal use. This breakthrough offers a sustainable alternative to harvesting rare wild agarwood, potentially helping both human health and forest conservation.

Genome Sequencing of Hericium coralloides by a Combination of PacBio RS II and Next-Generation Sequencing Platforms

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Scientists successfully sequenced the complete genome of Hericium coralloides, a medicinal mushroom used in traditional Chinese medicine for treating heart disease, cancer, and stomach problems. Using advanced sequencing technology combining long-read and short-read methods, they assembled the 55 million base pair genome containing over 11,700 genes. This genetic blueprint reveals the mushroom contains genes for producing beneficial enzymes and compounds with therapeutic potential. This milestone opens the door for future research to develop new medicines based on this mushroom’s natural bioactive properties.

Assessment of the Antitumor Activity of Green Biosynthesized Zinc Nanoparticles as Therapeutic Agent Against Renal Cancer in Rats

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Researchers created tiny zinc nanoparticles using an edible white mushroom through an environmentally friendly process. When tested in rats with kidney cancer, these nanoparticles significantly reduced tumor markers, protected kidney cells from oxidative damage, and triggered cancer cell death. The treatment improved kidney function and showed no toxic effects, suggesting it could be a promising new therapy for kidney cancer.

Edible Mushrooms and Beta-Glucans: Impact on Human Health

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Mushrooms contain compounds called β-glucans that can help boost your immune system and reduce inflammation. These compounds show promise in cancer treatment when combined with conventional therapies and may help fight infections. While mushrooms have long been used in traditional medicine, modern research is confirming their health benefits and understanding how they work in the body.

Clinical benefits of β-glucan supplementation in children: a review

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This review examines how β-glucan, a natural fiber found in mushrooms, yeast, and grains, can help strengthen children’s immune systems and improve their health. Studies show that β-glucan supplementation may reduce the frequency and severity of colds and respiratory infections, improve digestive health, help control blood sugar levels, and support overall development. The evidence suggests that β-glucan could be a valuable dietary supplement for malnourished or immunocompromised children worldwide.

Identification of matB used as an endogenous reference gene for the qualitative and real-time quantitative polymerase chain reaction detection of Lentinus edodes

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This study identifies the matB gene as a reliable genetic marker for detecting shiitake mushrooms (Lentinus edodes) in food products. Researchers developed a simple DNA test that can identify L. edodes in processed foods where it might be fraudulently substituted for more expensive wild mushrooms. The test is highly sensitive, detecting DNA at extremely low concentrations, and works on both raw mushrooms and processed products. This method provides food manufacturers and regulators with an effective tool to prevent mushroom fraud and ensure food authenticity.

therapeutic action: antitumor activity