antitumor activity – Page 2

Insights into the evolution and mechanisms of response to heat stress by whole genome sequencing and comparative proteomics analysis of the domesticated edible mushroom Lepista sordida

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Researchers sequenced the complete genome of Lepista sordida, a delicious edible mushroom valued for its health benefits, and studied how this mushroom responds to heat stress at the molecular level. Using advanced analysis techniques, they identified key proteins and signaling pathways that help the mushroom survive high temperatures. These findings can help farmers develop better-performing strains that are more resistant to heat, improving mushroom production.

Edible Mushrooms as Functional Ingredients for Development of Healthier and More Sustainable Muscle Foods: A Flexitarian Approach

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This comprehensive review explains how edible mushrooms can be added to meat and fish products to make them healthier and more environmentally friendly. Mushrooms are rich in protein, fiber, vitamins, and natural compounds that fight disease and prevent spoilage. By replacing part of the meat with mushrooms, food makers can create products with better nutrition, longer shelf-life, and reduced salt content, while supporting those pursuing flexitarian diets.

In vitro fermentation characteristics and prebiotic activity of herbal polysaccharides: a review

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This review explores how plant-based polysaccharides from traditional herbs can benefit our health by feeding good bacteria in our gut. When these polysaccharides are fermented by our gut microbiota, they break down into smaller compounds that produce short-chain fatty acids, which have anti-inflammatory and immune-boosting effects. The research shows that different herbs have different structures that are recognized by specific beneficial bacteria, which suggests we can develop personalized functional foods tailored to promote specific health benefits.

Current Uses of Mushrooms in Cancer Treatment and Their Anticancer Mechanisms

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This comprehensive review examines how medicinal mushrooms can help treat cancer. Certain mushroom species and their compounds, particularly polysaccharides, can boost the immune system to fight cancer cells, reduce chemotherapy side effects, and overcome drug resistance. Multiple mushrooms are currently in clinical trials showing promise in improving cancer patient outcomes when used alongside conventional treatments.

In vitro antitumor effects of methanolic extracts of three Ganoderma mushrooms

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Researchers tested extracts from three types of medicinal mushrooms (Ganoderma) against cancer cells in laboratory tests. They found that one species was particularly effective against liver cancer cells, while two other species worked well against breast cancer cells. The extracts killed cancer cells while being much less harmful to normal cells, suggesting they could potentially be developed into new cancer treatments.

Whole genome sequencing and annotations of Trametes sanguinea ZHSJ

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Scientists have completely mapped the genetic code of Trametes sanguinea, a medicinal mushroom used in traditional Chinese medicine. They identified over 10,000 genes and analyzed how this mushroom produces compounds that fight tumors, boost immunity, protect the heart, and fight viruses. This genetic map will help researchers understand how to produce these beneficial compounds and develop new medicines from this mushroom.

Enhancing the Yield of Pleurotus ostreatus Through the Addition of Nucleotides and Nucleosides

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Researchers discovered that adding nucleotides and nucleosides to oyster mushroom growing medium significantly increases mushroom yield and nutritional value. These compounds enhanced the dietary fiber and amino acid content while helping the mushrooms break down tough plant materials more efficiently. The study suggests that nucleosides are particularly effective and could provide a simpler, safer alternative to traditional mushroom cultivation methods that involve lengthy composting processes.

Evidence for the Existence of Mating Subtypes Within the Schizophyllum commune: Mating Behavior and Genetic Divergence

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Researchers discovered that a common fungus called Schizophyllum commune has hidden genetic subtypes within its mating types that weren’t recognized before. By studying 149 fungal strains and analyzing their mating behavior, they found that fungi with the same mating type could still behave differently when reproducing. Specific genes controlling pheromone chemicals were identified as responsible for these differences, revealing more complexity in fungal reproduction than previously understood.

Beta-Glucans from Fungi: Biological and Health-Promoting Potential in the COVID-19 Pandemic Era

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This article reviews how beta-glucans, natural compounds found in mushrooms, can boost your immune system and help fight diseases including COVID-19. These compounds work by activating immune cells and reducing dangerous inflammatory responses in the body. Mushroom beta-glucans are safe, easy to take by mouth, and available in many edible mushroom varieties like shiitake and oyster mushrooms.

Research Progress of Polysaccharide-Gold Nanocomplexes in Drug Delivery

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Scientists are combining polysaccharides (natural compounds found in plants and organisms) with tiny gold particles to create better drug delivery systems. These hybrid nanoparticles can transport medicines directly to cancer cells while reducing side effects and improving treatment effectiveness. The review discusses how these gold-polysaccharide combinations can also fight bacteria and viruses, making them useful for various medical applications beyond cancer therapy.

therapeutic action: antitumor activity