therapeutic action: antioxidant

Biodiversity-Driven Natural Products and Bioactive Metabolites

This comprehensive review explores how diverse organisms like plants, fungi, and marine creatures produce remarkable chemical compounds for survival and defense. These natural products have inspired many modern medicines, but scientists now understand that the chemical diversity comes not just from the organisms themselves but from their ecological interactions and environmental challenges. By studying how these chemicals are made and what triggers their production, researchers can discover new drugs and medicines while protecting the ecosystems that generate them.

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Chemical Composition and In Vitro Biological Activity of the Polar and Non-Polar Fractions Obtained from the Roots of Eleutherococcus senticosus (Rupr. et Maxim.) Maxim

Siberian ginseng (Eleutherococcus senticosus) roots contain powerful antioxidant compounds that may help with inflammation, blood sugar control, and brain health. Researchers found that certain plant fractions were particularly rich in protective compounds like chlorogenic acid and caffeic acid. However, the study also discovered a concerning finding: these plant compounds protected cancer cells from chemotherapy drugs, suggesting people undergoing cancer treatment should be cautious about using this supplement.

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Antioxidant Potential-Rich Betel Leaves (Piper betle L.) Exert Depigmenting Action by Triggering Autophagy and Downregulating MITF/Tyrosinase In Vitro and In Vivo

This research shows that betel leaves, a traditional herb used in Asian cultures, can lighten skin pigmentation through multiple mechanisms. The extract works by reducing tyrosinase enzyme activity, activating cellular cleanup processes called autophagy, and boosting the body’s natural antioxidant defenses. In both laboratory cells and living mice exposed to UV radiation, betel leaves extract effectively reduced unwanted skin darkening, suggesting it could be developed into safe natural skin-whitening products.

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Morphological and Phylogenetic Characterization of Endophytic Fungi Isolated from Brown Algae (Phaeophyceae) in Korea

Researchers in Korea discovered three previously unknown fungal species living inside brown seaweed called Sargassum. These fungi were identified using genetic analysis and microscopy. The discovery suggests that seaweed hosts diverse fungal communities that could have useful properties, such as producing compounds with antimicrobial and anti-cancer potential. This research expands our understanding of marine fungal diversity and its possible applications in medicine and biotechnology.

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Recent Discoveries on Marine Organism Immunomodulatory Activities

Scientists are discovering that creatures from the ocean produce powerful substances that can help our immune system fight diseases like cancer and inflammation. These marine organisms—from tiny algae to sponges to fish—create natural compounds that can either boost or calm down our immune response depending on what we need. Several of these ocean-derived medicines are already approved for treating serious diseases, and many more are being tested in clinical trials. The ocean covers 70% of our planet and most of it remains unexplored, suggesting there are many more beneficial compounds waiting to be discovered.

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Centesimal Composition, Bioactive Compounds, Antioxidant and α-Glucosidase Inhibitory Activities of Commercial Edible Oyster Mushrooms at Different Maturity Stages in Northern Thailand

This research studied five types of oyster mushrooms grown in Thailand at different stages of maturity. Researchers found that the nutritional content and beneficial compounds in mushrooms change as they grow. Young and middle-stage mushrooms had the highest levels of compounds that fight disease and help manage blood sugar, while fully mature mushrooms had more total nutrients. This information helps farmers decide when to harvest mushrooms based on whether customers want maximum nutrition or maximum health-promoting properties.

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The Genus Cordyceps Sensu Lato: Their Chemical Constituents, Biological Activities, and Therapeutic Effects on Air Pollutants Related to Lung and Vascular Diseases

Cordyceps mushrooms have been used in traditional Chinese medicine for centuries and are now being studied scientifically for their potential health benefits. These mushrooms contain powerful compounds that may help protect our lungs from air pollution effects and support heart health. Recent clinical studies show promising results for treating conditions like COPD, asthma, and even improving athletic performance in healthy people.

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Haplotype-resolved genomes of Phlebopus portentosus reveal nuclear differentiation, TE-mediated variation, and saprotrophic potential

Researchers sequenced the complete genomes of two compatible versions of the black truffle fungus Phlebopus portentosus, the only Boletales species grown commercially. They discovered that jumping genes called transposable elements cause significant differences between the two fungal nuclei, affecting the production of beneficial compounds. The study shows this mushroom can both partner with tree roots and break down organic matter independently, making it versatile in nature and valuable for both food and medicine.

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Innovative applications and therapeutic potential of oilseeds and their by-products: An eco-friendly and sustainable approach

This review explains how leftover materials from oilseed processing, which are usually discarded as waste, contain valuable nutrients and healing compounds. These by-products can be used to make healthier foods like bread, burgers, and drinks, or turned into supplements and medicines. By using these materials instead of wasting them, we can reduce environmental problems, provide better nutrition, and create sustainable food products that help prevent diseases like diabetes and heart problems.

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Transcriptome and Metabolome Integration Reveals the Impact of Fungal Elicitors on Triterpene Accumulation in Sanghuangporus sanghuang

Scientists studied how a special fungal treatment can boost the production of beneficial compounds in sanghuang mushrooms. Using advanced molecular analysis techniques, they found that the fungal elicitor significantly increased levels of healing compounds called triterpenes. The treated mushrooms produced 114 times more of one specific compound compared to untreated mushrooms. This research shows how we can grow medicinal mushrooms with higher levels of beneficial substances, which could help develop better treatments for various diseases.

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