therapeutic action: antioxidant response

Aspergillus fumigatus dsRNA virus promotes fungal fitness and pathogenicity in the mammalian host

Researchers discovered that a virus infecting the dangerous fungus Aspergillus fumigatus actually helps the fungus survive and cause worse infections in humans. By removing the virus from fungal strains, scientists found that the fungus became weaker and less able to cause disease in mice. Importantly, treating infected mice with an antiviral drug (ribavirin) reduced the viral load and helped the mice survive, suggesting a new approach to treating serious fungal infections.

Read More »

The Zn(II)2-Cys6-type zinc finger protein AoKap7 is involved in the growth, oxidative stress and kojic acid synthesis in Aspergillus oryzae

Researchers studied a protein called AoKap7 in a fungus used to produce kojic acid, which is found in many cosmetic and food products. By deleting this protein gene, they found that fungi grew faster but produced much less kojic acid and were more sensitive to stress. The protein works as a master switch that controls both how fast the fungus grows and how much of the valuable kojic acid it makes.

Read More »
Scroll to Top