therapeutic action: Antioxidant effects

Global research hotspots and trends in oxidative stress-related diabetic nephropathy: a bibliometric study

This study analyzed over 4,000 research papers published between 2014 and 2024 about how oxidative stress damages kidneys in diabetic patients. Researchers found that China and the United States lead this research field, with increasing focus on natural compounds and traditional medicines that can reduce harmful reactive oxygen species. The findings suggest future treatments for diabetic kidney disease should target oxidative stress through both conventional drugs and natural antioxidant compounds derived from plants and fungi.

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The putatively high‐altitude adaptation of macaque monkeys: Evidence from the fecal metabolome and gut microbiome

This study examined how macaque monkeys living on the high Tibetan Plateau adapt to harsh conditions. Researchers found that high-altitude macaques have darker feces containing more stercobilin, a pigment from red blood cell breakdown. Their gut bacteria are specially adapted to process this increased bilirubin from the extra red blood cells produced at high altitude. Interestingly, high-altitude macaques also eat medicinal mushrooms like Ganoderma lucidum, which may help them cope with the stress and low oxygen levels.

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Exploring the health benefits of Ganoderma: antimicrobial properties and mechanisms of action

Ganoderma is a medicinal mushroom that has been used in traditional medicine for thousands of years and shows promise as a natural antibiotic. The mushroom contains special compounds like polysaccharides and triterpenoids that can kill harmful bacteria and fungi by damaging their cell walls and boosting your immune system. Recent research shows it works against common infections like those caused by staph bacteria and E. coli, and may even help fight antibiotic-resistant germs.

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Characterizing flavor determinants and α-glucosidase inhibitory components in ancient tea plants and ‘Qiancha 1’ white teas

Researchers compared white teas made from ancient tea plants (over 100 years old) with modern cultivated tea varieties. The ancient teas had stronger floral aromas and more bitter taste due to higher levels of beneficial compounds. These compounds, particularly trans-β-ionone and β-damascenone, may help regulate blood sugar levels, making ancient tea plants valuable for both flavor and potential health benefits.

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Construction of a genetic linkage map and detection of quantitative trait locus for the ergothioneine content in tamogitake mushroom (Pleurotus cornucopiae var. citrinopileatus)

Researchers created the first genetic map of tamogitake mushrooms to identify genes controlling ergothioneine content. Ergothioneine is an antioxidant compound that provides health benefits like fighting inflammation and protecting brain health. They found one key genetic marker that reliably predicts which mushrooms will have high ergothioneine levels, enabling farmers to selectively breed mushrooms with enhanced health benefits.

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A characteristic rash caused by Shiitake mushrooms – An emerging concern?

Eating raw or undercooked Shiitake mushrooms can cause a distinctive whip-like rash in some people called Shiitake mushroom dermatitis. This dramatic rash appears 2-5 days after consumption but is not dangerous and goes away on its own in 10-14 days. The condition is caused by a compound called Lentinan that breaks down when mushrooms are cooked at higher temperatures, so properly cooking Shiitake mushrooms prevents the reaction.

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Specific Foods Associated with Depressive Symptoms among Young Adults and Their Bioactive Effects

This research examined how specific everyday foods like milk, eggs, bananas, oranges, sweet potatoes, mushrooms, and kimchi may help reduce depression symptoms in young adults. The study found that people eating more of these foods had significantly lower rates of depression. These foods contain natural compounds like vitamins, minerals, and antioxidants that support brain health and mood regulation. While more research is needed, the findings suggest that dietary choices could be an important part of managing depression.

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Positive interaction between melatonin and methyl jasmonate enhances Fusarium wilt resistance in Citrullus lanatus

Researchers discovered that two natural plant signaling molecules, melatonin and methyl jasmonate, work together to protect watermelons from a devastating fungal disease called Fusarium wilt. When applied to watermelon plants at the right concentrations, these molecules trigger the plant’s natural defense mechanisms, making the plants more resistant to infection. The study shows these compounds can be used as natural, sustainable alternatives to chemical pesticides for protecting crops.

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Multiomics Provides a New Understanding of the Effect of Temperature Change on the Fermentation Quality of Ophiocordyceps sinensis

This research studied how temperature affects the growth and quality of Ophiocordyceps sinensis, a valuable medicinal fungus. Scientists found that the fungus grows best between 18-23°C, and that temperatures above 28°C damage the fungus by triggering cell death processes. The study identified which genes and metabolites are affected by temperature changes, helping optimize large-scale production of this medicinal fungus.

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