therapeutic action: Antioxidant effects

Effects and safety of Psilocybe cubensis and Panaeolus cyanescens magic mushroom extracts on endothelin-1-induced hypertrophy and cell injury in cardiomyocytes

Researchers tested whether magic mushrooms containing psilocybin could be safely used by people with heart failure, especially those dealing with depression. Using laboratory rat heart cells, they found that extracts from Psilocybe cubensis and Panaeolus cyanescens mushrooms actually protected heart cells from damage and reduced harmful inflammation. The mushroom extracts worked similarly to standard heart medications at the tested concentrations, suggesting they may be safe for use under controlled medical supervision.

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The Potential of Naturally Derived Compounds for Treating Chronic Kidney Disease: A Review of Autophagy and Cellular Senescence

This review explores how natural products from traditional Chinese medicine may help treat chronic kidney disease by targeting two key aging processes: autophagy (cellular self-cleaning) and cellular senescence (cellular aging). Common natural compounds like curcumin, green tea extract, and Astragalus have shown promise in protecting kidney function and reducing harmful inflammation. While these natural treatments show potential as complementary therapies alongside mainstream medicines, more clinical research is needed to confirm their effectiveness and determine optimal dosages.

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Potential Roles of Exogenous Proteases and Lipases as Prebiotics

This review explores how digestive enzymes like proteases and lipases work similarly to prebiotics—foods that feed beneficial bacteria in your gut. When animals consumed supplements of these enzymes, their gut bacteria became healthier, producing more beneficial compounds and showing improved intestinal health. These findings suggest that fermented foods and raw foods containing natural digestive enzymes, as well as enzyme supplements, may help promote a healthy gut microbiome.

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Valorization of Mushroom Residues for Functional Food Packaging

Mushrooms produce large amounts of waste during growth and processing, but these leftovers contain valuable compounds that can protect food and extend shelf life. Scientists are developing ways to extract these beneficial compounds and add them to eco-friendly packaging films, creating materials that fight bacteria and oxidation naturally. This approach transforms mushroom waste into useful products while reducing environmental pollution, making food packaging safer and more sustainable for consumers.

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Antifungal activities of Rosmarinus extracts against Fusarium oxysporum, the pathogenic fungus of Anoectochilus stem rot

Researchers found that extracts from rosemary plants can effectively fight a fungus that causes stem rot disease in Anoectochilus, a valuable medicinal herb. The rosemary extracts worked both in laboratory tests and when applied to infected plants, reducing disease symptoms and boosting the plant’s natural defense mechanisms. These findings suggest rosemary extracts could be developed as a natural, safer alternative to synthetic chemical fungicides that harm the environment.

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Synbiotic yogurt with nanoparticle entrapped rice straw hemicellulose for immediate probiotic support and prebiotic delivery

Scientists created a new type of yogurt that contains beneficial bacteria and special prebiotics from rice straw. The innovation uses tiny nanoparticles to protect some of the prebiotics so they reach your gut intact, while free prebiotics immediately feed the beneficial bacteria in the yogurt during storage. This dual-delivery approach keeps the yogurt fresher longer while ensuring you get maximum health benefits for your digestive system.

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Attributes of Culture Bacteria as Influenced by Ingredients That Help Treat Leaky Gut

Researchers tested whether eight natural ingredients commonly used to treat leaky gut would affect the beneficial bacteria used to make yogurt. They found that ingredients like marshmallow root, licorice root, and slippery elm bark not only didn’t harm the yogurt bacteria but actually made them more resistant to stomach acid and bile. This means these ingredients could be safely added to yogurt to boost both the probiotic bacteria and the gut-healing properties of the product.

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Comparative Transcriptome Profiles of the Response of Mycelia of the Genus Morchella to Temperature Stress: An Examination of Potential Resistance Mechanisms

Scientists studied how morel mushrooms respond to different temperatures to understand why cultivation can be unpredictable. By analyzing gene activity in mushroom mycelia (the underground filaments) at temperatures from 5°C to 30°C, they found that 15-20°C was ideal for growth. At higher temperatures, the mushrooms showed signs of stress similar to heat damage in other organisms, turning brownish and activating protective genes. This research helps mushroom farmers optimize growing conditions for better yields.

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Dietary Phytochemicals in Cardiovascular Disease Prevention and Management: A Comprehensive Review

This review examines how plant-based compounds called phytochemicals can help prevent and manage heart disease. These compounds, found in foods like berries, nuts, tea, garlic, and whole grains, work through multiple mechanisms including reducing inflammation, lowering cholesterol, and improving blood vessel function. The review highlights that while pharmaceutical treatments exist, dietary approaches using phytochemical-rich foods offer a cost-effective and sustainable way to support heart health.

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In vitro antitumor effects of methanolic extracts of three Ganoderma mushrooms

Researchers tested extracts from three types of medicinal mushrooms (Ganoderma) against cancer cells in laboratory tests. They found that one species was particularly effective against liver cancer cells, while two other species worked well against breast cancer cells. The extracts killed cancer cells while being much less harmful to normal cells, suggesting they could potentially be developed into new cancer treatments.

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