therapeutic action: antimicrobial

Comparative transcriptome analysis reveals the genetic basis underlying the biosynthesis of polysaccharides in Hericium erinaceus

Researchers studied six different strains of lion’s mane mushrooms to understand how they produce beneficial compounds called polysaccharides. Using advanced genetic analysis, they identified thirteen key genes responsible for making these health-promoting molecules. The study found that a strain called PZH-05 produced the most polysaccharides, and its genes were more active than in other strains. This research helps explain why lion’s mane mushrooms are effective for boosting immunity, fighting cancer, and managing blood sugar.

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Advances in Fungal Natural Products: Insights into Bioactivity and Therapeutic Potential

Medicinal mushrooms and fungi contain powerful natural chemicals that can boost immunity, reduce inflammation, fight cancer, and protect the brain. Scientists are now better able to identify and study these compounds using advanced techniques, and some are being tested as supplements or alongside traditional medicines. This research shows that mushrooms could become important tools in treating diseases like inflammatory bowel disease, rheumatoid arthritis, and cancer.

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Proteins from Edible Mushrooms: Nutritional Role and Contribution to Well-Being

Mushrooms are highly nutritious foods containing proteins as complete and high-quality as meat, with unique compounds that boost immunity, fight infections, and may help prevent diseases like cancer and diabetes. Different types of mushroom proteins have specific health benefits, from strengthening immune systems to lowering blood pressure and fighting viruses. Scientists are finding new ways to grow mushrooms and extract their proteins for use in sports nutrition, medicines, and fortified foods, making them increasingly valuable for human health and sustainability.

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Whole genome sequencing and annotations of Trametes sanguinea ZHSJ

Scientists sequenced the complete genome of Trametes sanguinea, a medicinal mushroom used in traditional Chinese medicine, grown in China. The mushroom’s tissue contains beneficial compounds that may help fight tumors, protect the heart, boost immunity, and heal diabetic wounds. By mapping out all 10,886 genes in this fungus, researchers now have detailed blueprints to understand how it produces these healing compounds and potentially grow them industrially for medical use.

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Endophytic Fungi Isolated from the Brown Alga Sargassum thunbergii in Coastal Korea

Researchers isolated six previously unknown fungal species living inside the brown seaweed Sargassum thunbergii collected from Korean coastal waters. These fungi, identified through genetic analysis and physical characteristics, belong to families known for producing compounds with antimicrobial and anti-inflammatory properties. The discovery reveals that seaweeds harbor a diverse community of fungi that could potentially be used to develop new medicines and agricultural products.

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Chemical Composition and Biological Activities of Psilocybe Mushrooms: Gaps and Perspectives

This review examined research on Psilocybe mushrooms and their chemical compounds, particularly psilocybin and psilocin, which show promise for treating depression and anxiety. The authors found that while these psychoactive compounds have been extensively studied, many other chemical substances in these mushrooms remain unexplored. Additionally, preliminary studies suggest these mushrooms may have antimicrobial and antioxidant properties, though more research is needed. The review highlights significant gaps in understanding the full potential of Psilocybe mushrooms for medical applications.

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The Benefits and Applications of Lactobacillus plantarum in Food and Health: A Narrative Review

Lactobacillus plantarum is a beneficial bacterium commonly found in fermented foods like yogurt and cheese that acts as a natural probiotic. It can help preserve food, improve flavor, and boost health by supporting digestion, strengthening immunity, and reducing inflammation. Research shows it may help with weight management, blood sugar control, and mental health, making it valuable for both the food industry and medical applications.

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Bioactivity and chemical screening of endophytic fungi associated with seaweeds Gracilaria sp. and Sargassum sp. of the Bay of Bengal, Bangladesh

Researchers discovered several types of fungi living inside seaweed from Bangladesh’s Bay of Bengal coast. These fungi produce natural compounds that can fight bacteria, reduce harmful oxidative damage, and potentially kill cancer cells. The study identified specific chemical compounds responsible for these beneficial properties, suggesting these fungi could be useful sources for developing new medicines.

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Lipid Fraction from Agaricus brasiliensis as a Potential Therapeutic Agent for Lethal Sepsis in Mice

Researchers tested a special extract from the Agaricus brasiliensis mushroom (rich in a compound called ergosterol) to treat severe sepsis, a life-threatening blood infection, in mice. When mice were given this mushroom extract alone, 67% survived, and when combined with antibiotics, 100% survived compared to none with saline alone. The extract reduced inflammation, protected the liver, fought bacteria, and reduced harmful free radicals in the body, suggesting it could be a valuable addition to antibiotic treatment for sepsis.

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New species and records of ascomycetes on cypress in Beijing, China

Researchers in Beijing investigated fungal diseases affecting cypress trees, which are important for landscaping and have medicinal value. They collected samples from diseased and healthy cypress parts and identified 13 different fungal species, including two completely new species and two species previously unknown on cypress trees. The study helps us understand the various fungi living on cypress trees, both harmful pathogens and potentially beneficial endophytic fungi that may have useful medicinal properties.

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