Antimicrobial activity – Page 8

A New Species and Eight New Records of Ascomycetes from Freshwater Niches in Korea

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Researchers discovered a brand new species of fungus and identified eight previously unknown fungal species living in freshwater environments across South Korea. These freshwater fungi play important roles in breaking down plant material and producing compounds with antimicrobial properties. The study used DNA analysis and traditional microscopy to identify and describe these fungi in detail, significantly expanding our knowledge of fungal diversity in Korean freshwater habitats.

Exploring the health benefits of Ganoderma: antimicrobial properties and mechanisms of action

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Ganoderma is a medicinal mushroom that has been used in traditional medicine for thousands of years and is now being studied for its ability to fight infections. The mushroom contains special compounds like polysaccharides and triterpenoids that can kill harmful bacteria and fungi in multiple ways—by breaking down their cell walls, stopping them from reproducing, and boosting your immune system. Scientists have found that Ganoderma works against many dangerous bacteria including antibiotic-resistant strains, and it may offer a natural alternative to conventional antibiotics as antibiotic resistance becomes a major global health problem.

Antifungal Effects of Pterostilbene on Candida albicans, Candida dubliniensis, and Microcosm Biofilms of Denture Stomatitis

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Pterostilbene, a natural compound found in blueberries and grapes, has been shown to effectively kill Candida fungi that cause denture-related mouth infections. In laboratory tests, it successfully eliminated fungal cells and disrupted harmful biofilms within 8 hours. When tested in a living organism model, pterostilbene proved safe and reduced infection severity, suggesting it could be a promising natural alternative to conventional antifungal medications.

Fruiting body-associated Pseudomonas contact triggers ROS-mediated perylenequinone biosynthesis in Shiraia mycelium culture

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Scientists discovered that bacteria living inside medicinal mushroom fruiting bodies can trigger the production of powerful healing compounds called perylenequinones through direct physical contact. These compounds are being used to fight cancer and harmful bacteria through a therapy called photodynamic therapy. The study shows that when bacteria touch the mushroom’s cells, it causes the mushroom to produce more of these therapeutic compounds by creating controlled stress that activates specific genes.

Streptomyces-Based Bioformulation to Control Wilt of Morchella sextelata Caused by Pestalotiopsis trachicarpicola

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Morels are valuable mushrooms threatened by fungal wilt disease in China. Researchers isolated two beneficial bacteria (Streptomyces) from morel soil that naturally fight the fungal disease. When applied to morel fields, these bacteria reduced disease and increased mushroom yield by 30% compared to untreated fields. This represents a natural, eco-friendly solution to protect morel crops and boost production without chemical fungicides.

Enhancement of Perylenequinonoid Compounds Production from Strain of Pseudoshiraia conidialis by UV-Induced Mutagenesis

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Researchers used UV light to mutate fungal strains that naturally produce powerful medicinal compounds called perylenequinones. These compounds show promise for treating cancer and viral infections through photodynamic therapy. Through careful mutagenesis and screening, they developed a superior fungal strain that produces over 2100 mg/L of these valuable compounds, far exceeding previous methods. The breakthrough highlights that focusing on multiple beneficial compounds rather than just one can lead to better commercial applications.

Biological applications of yttrium oxide nanocomposites synthesized from Aspergillus penicillioides and their potential role in environmental remediation

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Researchers used a fungus called Aspergillus penicillioides to create tiny particles of yttrium oxide that can remove dangerous metals like lead and nickel from contaminated water. These particles work like microscopic sponges that grab onto the toxic metals when exposed to UV light. The particles also kill bacteria and fight harmful free radicals, making them useful for both cleaning water and potentially treating infections.

Functionalized Micellar Membranes from Medicinal Mushrooms as Promising Self-Growing Bioscaffolds

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Scientists created special membranes from medicinal mushrooms that can help heal wounds and regenerate damaged skin. These membranes are grown naturally in liquid culture and enriched with extract from mango peels to fight bacteria and promote healing. The material is completely natural, biodegradable, and performs better than many conventional wound healing materials, making it an eco-friendly option for medical applications.

Harnessing pycnidia-forming fungi for eco-friendly nanoparticle production, applications, and limitations

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Certain fungi called pycnidial fungi can create tiny particles called nanoparticles that are useful in medicine, agriculture, and environmental cleanup. These fungi naturally produce chemicals and enzymes that reduce metal ions into nanoparticles, which have antimicrobial and cancer-fighting properties. While this biological approach is more environmentally friendly than chemical methods, scientists still need to solve challenges like making it work at large scales and ensuring the nanoparticles are safe and stable.

Research Progress of Polysaccharide-Gold Nanocomplexes in Drug Delivery

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Scientists are combining polysaccharides (natural compounds found in plants and organisms) with tiny gold particles to create better drug delivery systems. These hybrid nanoparticles can transport medicines directly to cancer cells while reducing side effects and improving treatment effectiveness. The review discusses how these gold-polysaccharide combinations can also fight bacteria and viruses, making them useful for various medical applications beyond cancer therapy.

therapeutic action: Antimicrobial activity