Antimicrobial activity – Page 5

Clinical Isolate of Candida tropicalis from a Patient in North Carolina: Identification, Whole-Genome Sequence Analysis, and Anticandidal Activity of Ganoderma lucidum

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Researchers in North Carolina identified a drug-resistant yeast infection (Candida tropicalis) from a hospital patient and tested whether extracts from reishi mushrooms (Ganoderma lucidum) could kill it. Using genetic analysis, they found mutations in the yeast that help it resist antifungal drugs. All three types of mushroom extracts tested successfully stopped the yeast’s growth and damaged its cells, suggesting that reishi mushrooms could be a promising natural treatment option for hard-to-treat candida infections.

Short-term effects of a synbiotic diet on thyroid and sex hormones in Sarabi Dogs

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Researchers tested whether a special dog food containing beneficial bacteria (L. acidophilus) and a type of fiber (inulin) would affect hormone levels in male Sarabi dogs. Over 24 days, dogs eating this special food showed no harmful changes in thyroid or sex hormones, and all hormone levels stayed normal. This suggests the synbiotic food could potentially be used long-term in dogs without worrying about negative hormonal effects.

Green-Synthesized Nanomaterials from Edible and Medicinal Mushrooms: A Sustainable Strategy Against Antimicrobial Resistance

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Scientists are developing a new weapon against antibiotic-resistant bacteria using mushrooms. These special nanoparticles derived from edible and medicinal mushrooms can kill harmful bacteria in multiple ways without the toxic chemicals used in traditional manufacturing. The nanoparticles work by disrupting bacterial membranes, creating harmful molecules called free radicals, and even boosting your body’s natural immune response. This environmentally friendly approach could become an important tool in fighting dangerous infections that don’t respond to current antibiotics.

Chemical Composition and Biological Activities of Psilocybe Mushrooms: Gaps and Perspectives

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This comprehensive review examined what we know about Psilocybe mushrooms, which are known for their mind-altering effects due to compounds called psilocybin and psilocin. The study found that while these mushrooms show promise for treating depression and anxiety, most research has focused only on their psychoactive properties. The review identified over 30 chemical compounds in these mushrooms and noted that some species show potential antimicrobial and antioxidant properties. The authors emphasize that much more research is needed to explore other potential health benefits and to understand exactly how individual compounds work in the body.

Marine-Derived Enterococcus faecalis HY0110 as a Next-Generation Functional Food Probiotic: Comprehensive In Vitro and In Vivo Bioactivity Evaluation and Synergistic Fermentation of Periplaneta americana Extract Powder

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Scientists discovered a beneficial bacteria called Enterococcus faecalis HY0110 from bluefin tuna that could help protect gut health and fight harmful pathogens better than current probiotics. This marine bacteria produces important compounds like acetic acid that kill disease-causing bacteria, reduce inflammation in inflammatory bowel disease, and even slows cancer cell growth. When fermented with cockroach powder, it creates powerful health-boosting compounds that could make functional foods more effective for managing digestive diseases and supporting overall wellness.

Geographic variation in fungal diversity associated with leaf spot symptoms of Coffea arabica in Yunnan, China

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Researchers studied the different types of fungi found on coffee plant leaves in two regions of Yunnan, China. They discovered that the mountainous areas of Pu’er had more harmful fungi causing leaf spot disease, while the tropical lowlands of Xishuangbanna had more beneficial fungi that could naturally control pests. This information helps coffee farmers choose better disease management strategies based on their location’s unique environmental conditions.

Synergistic potential and apoptosis induction of Bunium persicum essential oil and its pure components, cuminaldehyde and γ-terpinene, in combination with fluconazole on Candida albicans isolates: in vitro and in silico evaluation

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Researchers tested a spice-derived essential oil called Bunium persicum and two of its active compounds to see if they could work better with the antifungal drug fluconazole against drug-resistant yeast infections. They found that one component called cuminaldehyde was particularly effective and worked synergistically with fluconazole, meaning the combination was more powerful than either treatment alone. These natural compounds could potentially help treat fungal infections that no longer respond to standard medications, offering a promising approach using plant-based remedies alongside conventional drugs.

Endophytic fungi isolated from Vietnamese nut grass (Cyperus rotundus L. Cyperaceae) – A promising solution to mitigate the prime phenomenon of antibiotic resistance

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Scientists discovered seven types of fungi living inside nut grass plants that can fight dangerous bacteria, including those resistant to current antibiotics. These fungi showed strong ability to kill drug-resistant staph bacteria and other serious pathogens. The findings suggest that these naturally-occurring fungi could be developed into new antibiotics to treat infections that currently have limited treatment options.

Rediscovery of viomellein as an antibacterial compound and identification of its biosynthetic gene cluster in dermatophytes

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Researchers discovered that skin-infecting fungi called dermatophytes produce a red pigment called viomellein that kills bacteria. By studying the genes responsible for making viomellein, scientists found that this compound may help dermatophytes establish infections by eliminating competing bacteria on the skin. This discovery could explain how these fungi successfully colonize human skin and may lead to new treatment strategies for stubborn fungal infections.

Native Bacteria Are Effective Biocontrol Agents at a Wide Range of Temperatures of Neofusicoccum parvum, Associated with Botryosphaeria Dieback on Grapevine

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Researchers from Chile identified native bacteria (specifically Pseudomonas strains) that effectively prevent a destructive fungal disease affecting grapevines. These bacteria can work across a wide range of temperatures and significantly reduce fungal growth both in laboratory tests and in actual vineyard conditions. This discovery offers an environmentally friendly alternative to chemical fungicides for protecting grapevines, particularly important as younger vines appear more vulnerable to infection.

therapeutic action: Antimicrobial activity