therapeutic action: Antimicrobial activity

Harnessing pycnidia-forming fungi for eco-friendly nanoparticle production, applications, and limitations

Scientists are using special fungi called pycnidial fungi to create tiny nanoparticles that could revolutionize medicine and environmental cleanup. These fungi naturally produce chemicals that can turn metal into useful nanoparticles without the toxic processes used in factories. The resulting nanoparticles show promise in fighting bacteria, cancer cells, and cleaning polluted water, offering a safer and more eco-friendly alternative to traditional methods.

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Four Unrecorded Species of Endophytic Diaporthe (Sordariomycetes) in Korea

Researchers in Korea discovered four new species of endophytic fungi called Diaporthe living inside plant tissues without causing visible disease. Using genetic testing and microscopic examination, they identified D. caryae, D. phoenicicola, D. stewartii, and D. unshiuensis as previously unrecorded in Korea. These fungi can potentially produce compounds with medicinal properties or help manage plant diseases. This discovery helps scientists better understand the hidden fungal diversity in Korean ecosystems.

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Microbial-Based Green Synthesis of Silver Nanoparticles: A Comparative Review of Bacteria- and Fungi-Mediated Approaches

Scientists are developing environmentally friendly ways to make silver nanoparticles using bacteria and fungi instead of harsh chemicals. These tiny particles show promise in fighting infections, treating cancer, cleaning water, and protecting crops. The review compares how bacteria and fungi each produce these particles and explains how different conditions affect their properties and effectiveness.

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Eco-friendly biosynthesis of silver nanoparticles using marine-derived Fusarium equiseti: optimization, characterization, and evaluation of antimicrobial, antioxidant, and cytotoxic activities

Scientists used a marine fungus called Fusarium equiseti to create tiny silver particles called nanoparticles in an environmentally-friendly way. These particles showed strong abilities to kill harmful bacteria and fungi, protect cells from damage caused by free radicals, and fight breast cancer cells in laboratory tests. This green synthesis method offers a safer, non-toxic alternative to traditional chemical manufacturing while producing stable, multi-functional nanoparticles.

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Ergostane-type steroids from mushrooms of Pleurotus genus

Oyster mushrooms and king trumpet mushrooms contain special compounds called ergostane-type steroids that have interesting chemical structures. These compounds can fight inflammation and may help with cancer. Scientists have discovered that some of these compounds have unique rearranged structures that don’t exist in other organisms. These mushroom-derived compounds show promise for developing new medicines.

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Deoxynucleosides as promising antimicrobial agents against foodborne pathogens and their applications in food and contact material surfaces

Researchers found that two nucleoside compounds (ddA and FdCyd) can effectively kill harmful bacteria like Vibrio and Salmonella that form slimy biofilms on seafood and food preparation surfaces. These compounds work by damaging bacterial cell membranes and preventing bacteria from communicating with each other. When combined with a food additive already used in the meat industry, these nucleosides become even more effective at much lower doses, potentially making food safer while reducing residual chemical effects.

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Editorial: Innovation in tackling the global challenge of eradicating antibiotic-resistant microorganisms

Antibiotic resistance is a serious global health problem causing millions of deaths annually. Scientists are developing new approaches to fight resistant bacteria, including using bacteriophages (viruses that attack bacteria), improving detection methods, and testing plant-based compounds. This editorial discusses 15 research papers showing various innovative strategies, emphasizing that we need multiple tools working together rather than relying on any single solution to solve this complex problem.

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Molecular Identification, Mycelial Growth Kinetics, and Antimicrobial Potential of Newly Isolated Medicinal Mushroom Fomitopsis pinicola from Bulgaria

Scientists isolated and studied a medicinal mushroom called Fomitopsis pinicola from Bulgaria. They confirmed its identity using DNA analysis and tested how well it grows on different nutrient media. The mushroom showed strong antimicrobial effects against disease-causing bacteria, especially when extracted with water, making it a promising candidate for developing new antibiotics to fight antibiotic-resistant infections.

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Encapsulation of progesterone in reishi mushroom composite for optimized hormone replacement and targeted anticancer therapy

Researchers created a new treatment by combining progesterone (a hormone) with reishi mushroom powder to make it work better in the body. The mushroom acts like a protective wrapper that slowly releases the hormone, making it more effective for treating menopausal symptoms and fighting breast cancer cells. The combination also fights harmful bacteria and fungi while remaining stable during storage. This approach combines traditional medicine with modern pharmaceutical science.

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Improving treatment of chromoblastomycosis: the potential of COP1T-HA and antimicrobial photodynamic therapy against Fonsecaea monophora in vitro

Chromoblastomycosis is a stubborn skin fungal infection that is difficult to treat with current medications and often comes back after treatment. Researchers tested a new treatment using a special light-activated compound called COP1T-HA combined with blue light, which successfully killed the fungus in laboratory tests. The treatment worked quickly and at low doses, showing promise as a potential new therapy for this challenging infection.

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