Antimicrobial activity – Page 10

Four Unrecorded Species of Endophytic Diaporthe (Sordariomycetes) in Korea

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Researchers in Korea discovered four previously unknown species of Diaporthe fungi living inside plant tissues without causing visible damage. These fungi were identified using genetic analysis and compared to known species from around the world. The findings show that Korea has more fungal diversity than previously documented and suggest these fungi could potentially be used to develop new medicines or help control plant diseases.

Ultrasound-Assisted Preparation of Chitosan Oligosaccharide-Stabilized Thyme Oil-in-Water Nanoemulsions: Enhanced Storage Stability and Antimicrobial Properties

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Researchers created tiny droplets of thyme oil mixed in water using sound waves and a natural stabilizer from shellfish shells. These droplets stayed stable for weeks without separating and worked twice as well at fighting bacteria and mold compared to regular thyme oil. The new formula could be used to keep fresh food from spoiling during storage.

Production of fungal hypocrellin photosensitizers: Exploiting bambusicolous fungi and elicitation strategies in mycelium cultures

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Hypocrellins are powerful compounds from fungi that can treat cancers and infections through light-activated therapy. Since wild sources are limited, scientists are growing these fungi in laboratory cultures and using special techniques to boost production. This review summarizes the best methods for producing hypocrellins, from choosing the right fungal strains to optimizing growing conditions and using natural stimulants to increase yields.

Genome Sequencing of Hericium coralloides by a Combination of PacBio RS II and Next-Generation Sequencing Platforms

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Scientists successfully sequenced the complete genome of Hericium coralloides, a medicinal mushroom used in traditional Chinese medicine for treating heart disease, cancer, and stomach problems. Using advanced sequencing technology combining long-read and short-read methods, they assembled the 55 million base pair genome containing over 11,700 genes. This genetic blueprint reveals the mushroom contains genes for producing beneficial enzymes and compounds with therapeutic potential. This milestone opens the door for future research to develop new medicines based on this mushroom’s natural bioactive properties.

Nutritional contents and antimicrobial activity of the culinary-medicinal mushroom Leccinum scabrum

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This study examined the health benefits of Leccinum scabrum, a mushroom used both as food and medicine. Researchers tested extracts from this mushroom against harmful bacteria and found they were very effective at stopping bacterial growth. The extracts were created using two different methods and both worked well, suggesting this mushroom could have practical antimicrobial applications.

Caseinate–Carboxymethyl Chitosan Composite Edible Coating with Soybean Oil for Extending the Shelf Life of Blueberry Fruit

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This study developed a special edible coating made from natural proteins and carbohydrate polymers with soybean oil to keep blueberries fresh longer. When blueberries were dipped in this coating and refrigerated, they lost less water, stayed firmer, and developed less mold compared to uncoated berries. The coating worked like an invisible protective layer that helped blueberries maintain their quality for up to 28 days, potentially reducing food waste and spoilage.

Exploring the health benefits of Ganoderma: antimicrobial properties and mechanisms of action

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Ganoderma is a medicinal mushroom that has been used in traditional medicine for thousands of years and shows promise as a natural antibiotic. The mushroom contains special compounds like polysaccharides and triterpenoids that can kill harmful bacteria and fungi by damaging their cell walls and boosting your immune system. Recent research shows it works against common infections like those caused by staph bacteria and E. coli, and may even help fight antibiotic-resistant germs.

The polyphasic approach reveals two new species and two new records of Nigrospora (Apiosporaceae, Amphisphaeriales) associated with Aquilaria sinensis from China

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Researchers discovered two previously unknown species of Nigrospora fungi (N. guangxiensis and N. pubeiensis) living inside agarwood tree leaves in southern China. These fungi, along with two other known species, were identified using a combination of microscopic examination and DNA analysis. The findings expand our understanding of fungal diversity in agarwood trees, which are valuable medicinal plants, and may have practical applications for the agarwood production industry.

Fungal-fungal cocultivation alters secondary metabolites of marine fungi mediated by reactive oxygen species (ROS)

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Researchers discovered that when two types of ocean fungi grow together, one of them produces a protective chemical called alternariol that can kill bacteria and cancer cells. This happens because the fungi recognize each other as competitors and trigger special stress signals that activate defensive chemical production. Interestingly, fungi from the ocean respond differently than those from land, suggesting they have evolved unique survival strategies for harsh marine environments.

Glucose-6-Phosphate Dehydrogenase Modulates Shiraia Hypocrellin A Biosynthesis Through ROS/NO Signaling in Response to Bamboo Polysaccharide Elicitation

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Researchers discovered that a naturally derived compound from bamboo boosts the production of hypocrellin A, a promising cancer-fighting and antimicrobial agent made by a special fungus. By studying a key enzyme called G6PDH, they found that it acts as a molecular switch controlling hypocrellin production when the fungus senses bamboo components. This discovery enables cost-effective large-scale production of this powerful medicine through simple fermentation, potentially making novel cancer treatments and antibiotics more accessible.

therapeutic action: Antimicrobial activity