antimicrobial – mycolab.ai

Medicinal Mushrooms: Bioactive Compounds, Use, and Clinical Trials

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This comprehensive review examines how medicinal mushrooms contain natural compounds that can boost immune function, fight cancer cells, reduce inflammation, and protect nerve cells. Different mushroom species like reishi, shiitake, and maitake contain various active substances such as beta-glucans and triterpenes that work through multiple biological pathways. While laboratory and animal studies show promising results, more human clinical trials are needed to confirm effectiveness and establish safe dosing guidelines.

Synthesis of fungal polysaccharide-based nanoemulsions for cancer treatment

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Researchers developed tiny capsules (nanoemulsions) made from corn protein and chitosan to better deliver shiitake mushroom compounds to treat cancer and reduce inflammation. When shiitake extract was enclosed in these nano-sized carriers, it became much more effective at killing breast cancer cells, fighting bacteria, and reducing inflammation compared to using the mushroom extract alone. This technology could lead to new natural medicines and health supplements that are more effective at lower doses.

Large-Scale Field Cultivation of Morchella and Relevance of Basic Knowledge for Its Steady Production

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Morels are valuable mushrooms worth hundreds of dollars per kilogram. China dramatically expanded morel farming from 2012 to 2022, but many farmers struggle with unstable harvests and profits. Scientists have discovered that successful morel cultivation requires careful attention to species selection, proper nutrition techniques, and understanding the complex mating systems of morel fungi. Better training and scientific knowledge could help make morel farming more reliable and profitable worldwide.

Six Unrecorded Species of Agaricales (Agaricomycetes, Basidiomycota) from Mudeungsan National Park in Korea

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Researchers discovered six previously unknown mushroom species in Mudeungsan National Park in southern Korea. These species were identified using both traditional microscopic examination and modern DNA analysis techniques. The findings show that despite being a major protected area, the park’s fungal diversity remains incompletely documented, suggesting more undiscovered species may exist there. Some of these mushrooms are notable for having bioactive properties with potential medicinal applications.

Exploring the Nutritional Value and Bioactive Potential of Craterellus cornucopioides (L.) Pers. as a Functional Food Source

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Black trumpet mushrooms from Romania have been found to contain high levels of beneficial compounds that protect cells from damage and fight harmful bacteria. The mushrooms showed strong antioxidant properties in laboratory tests and were effective against several disease-causing bacteria, though not against all types tested. These results suggest that black trumpets could be used as a natural supplement or food ingredient to support health and potentially help treat infections.

Comprehensive review on oyster mushroom species (Agaricomycetes): Morphology, nutrition, cultivation and future aspects

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Oyster mushrooms are increasingly popular edible fungi that can be grown on agricultural waste materials like rice and wheat straw. These nutritious mushrooms are rich in protein, vitamins, and minerals while containing compounds with health benefits including antioxidant and anti-inflammatory properties. Their cultivation offers an environmentally friendly solution to waste management while producing highly nutritious food that could help address global food security challenges.

Solid-state fermentation as a strategy for improvement of bioactive properties of the plant-based food resources

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This review explains how fermentation—a natural biological process—can enhance the health-promoting compounds in plant-based foods. By using specific fungi and bacteria on solid plant materials, scientists can increase beneficial antioxidants and proteins that may help prevent chronic diseases. This method is more environmentally friendly and cost-effective than traditional extraction techniques, making nutritious plant foods even healthier.

In vitro assessment of multipotential therapeutic importance of Hericium erinaceus mushroom extracts using different solvents

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This research examined how Lion’s Mane mushroom extracts made with different liquids can fight infections and oxidative damage. The water-based extract was best at preventing viruses and free radical damage, while the ethyl acetate extract worked best against bacteria and fungi. The study identified 16 beneficial compounds in the mushroom and suggests it could be used as a daily supplement to protect against infections and oxidative stress.

Olive mill solid waste induces beneficial mushroom-specialized metabolite diversity revealed by computational metabolomics strategies

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This study shows how adding olive mill waste to mushroom growing substrate can increase beneficial compounds in mushrooms while reducing harmful toxins. Researchers grew two types of edible mushrooms (lion’s mane and king oyster) on substrate containing different amounts of olive mill waste and used advanced chemical analysis to identify how the waste affected the mushrooms’ medicinal compounds. Adding olive mill waste increased healthy compounds like hericenones and erinacerins while decreasing toxic enniatin compounds, potentially creating safer and more nutritious mushrooms for consumers.

A multilocus phylogeny of Hericium (Hericiaceae, Russulales)

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Researchers conducted the first comprehensive genetic study of lion’s mane mushrooms (Hericium species) using advanced DNA sequencing techniques. The study resolved long-standing confusion about different species and their relationships, while also describing a new species from western North America. These mushrooms are prized both as food and for traditional medicinal uses, particularly in Asia, and contain compounds with potential anti-inflammatory, antimicrobial, and neuroprotective properties. Better identification of species will help both commercial cultivators and medical researchers work with the correct organisms.

therapeutic action: antimicrobial