therapeutic action: antifungal treatment with amphotericin B

Neonatal Invasive Candidiasis: Current Concepts

Neonatal invasive candidiasis is a serious fungal infection affecting premature and very low birth weight babies. The types of fungi causing these infections are changing globally, with more resistant strains appearing, especially in lower-income countries. Treatment options are limited by this resistance, making prevention through hygiene and proper hospital practices increasingly important.

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Distribution of fungal agents in the respiratory system of patients with underlying lung diseases; molecular identification and antifungal susceptibility profiles

This research examined fungal infections in hospitalized patients with lung diseases in Iran, identifying which fungi were most common and which antifungal medications worked best against them. Researchers found that Candida albicans and Aspergillus flavus were the most prevalent fungi, particularly in COPD patients. Notably, some Candida isolates showed resistance to certain antifungal drugs, particularly voriconazole. The study emphasizes the importance of proper fungal identification and susceptibility testing for effective treatment.

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