antifungal effects – mycolab.ai

The Transformation and Protein Expression of the Edible Mushroom Stropharia rugosoannulata Protoplasts by Agrobacterium-tumefaciens-Mediated Transformation

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Scientists developed a genetic engineering technique to modify king stropharia (a cultivated edible mushroom) by inserting foreign genes into its cells. This breakthrough allows researchers to study how the mushroom grows and produces beneficial compounds. The technique uses a bacterium called Agrobacterium tumefaciens to naturally deliver genes into mushroom cells, similar to how it infects plants. This advancement could lead to improved cultivation practices and enhanced nutritional or medicinal properties.

Valorization of Mushroom Residues for Functional Food Packaging

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Mushrooms produce large amounts of waste during growth and processing, but these leftovers contain valuable compounds that can protect food and extend shelf life. Scientists are developing ways to extract these beneficial compounds and add them to eco-friendly packaging films, creating materials that fight bacteria and oxidation naturally. This approach transforms mushroom waste into useful products while reducing environmental pollution, making food packaging safer and more sustainable for consumers.

Clinical Isolate of Candida tropicalis from a Patient in North Carolina: Identification, Whole-Genome Sequence Analysis, and Anticandidal Activity of Ganoderma lucidum

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Researchers in North Carolina identified a drug-resistant yeast infection (Candida tropicalis) from a hospital patient and tested whether extracts from reishi mushrooms (Ganoderma lucidum) could kill it. Using genetic analysis, they found mutations in the yeast that help it resist antifungal drugs. All three types of mushroom extracts tested successfully stopped the yeast’s growth and damaged its cells, suggesting that reishi mushrooms could be a promising natural treatment option for hard-to-treat candida infections.

In vitro and in vivo inhibitory effects and transcriptional reactions of graphene oxide on Verticillium dahliae

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Scientists discovered that graphene oxide, a nanomaterial, can effectively kill or inhibit the growth of Verticillium dahliae, a harmful fungus that causes wilt disease in cotton and other crops. The graphene oxide works by damaging the fungus’s cell membranes and disrupting its ability to grow and spread. When applied to cotton plants infected with this fungus, graphene oxide treatment reduced disease symptoms and prevented the fungus from multiplying. This research suggests graphene oxide could become a valuable alternative to chemical fungicides for controlling this destructive plant disease.

Safety and efficacy of the swift microwave device in patients with mild-to-moderate onychomycosis: Protocol of an open-label, randomized, dose-finding pilot study

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This study evaluates a new microwave device (Swift System) as a potential treatment for fungal nail infections (onychomycosis). The device uses microwave energy to heat and eliminate fungal infections directly at the nail site, avoiding the side effects of oral medications. Researchers tested three different treatment schedules in 39 patients over 12 months to find the most effective dosing approach.

Combination of Q-switched 1,064 and 532 nm Nd: YAG laser in the treatment of toenail onychomycosis: a pilot study

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This study tested a laser treatment using two different wavelengths (1,064 and 532 nanometers) to treat toenail fungal infections. Fifteen patients with toenail fungus received eight weekly laser sessions. The treatment was safe and worked best for mild cases, curing 100% of them, but was less effective for severe infections. Although patients experienced some pain during treatment, the overall results suggest laser therapy could be a useful option for treating mild fungal toenail infections without the side effects of oral medications.

Phylogeny of Aspergillus section Circumdati and inhibition of ochratoxins potential by green synthesised ZnO nanoparticles

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Researchers identified four species of Aspergillus fungus that contaminate crops and produce poisonous compounds called ochratoxins. They found that specially made zinc oxide nanoparticles, created using an environmentally friendly method with basil extract, can significantly reduce the amount of ochratoxins produced by these fungi. This discovery could help protect agricultural products from contamination and improve food safety.

The Transformation and Protein Expression of the Edible Mushroom Stropharia rugosoannulata Protoplasts by Agrobacterium-tumefaciens-Mediated Transformation

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Researchers successfully developed a method to genetically modify the edible mushroom Stropharia rugosoannulata using Agrobacterium tumefaciens bacteria. This technique allows scientists to insert and express foreign genes in the mushroom, providing tools to study how specific genes control mushroom growth and the production of health-promoting compounds. The study demonstrates that both artificial and natural resistance markers can be used to identify successfully transformed mushrooms, offering a foundation for improving mushroom cultivation and breeding.

therapeutic action: antifungal effects