therapeutic action: antifungal activity

Essential Oils as an Antifungal Alternative for the Control of Various Species of Fungi Isolated from Musa paradisiaca: Part I

Researchers tested six common cooking and medicinal herbs in oil form to see if they could kill fungi that damage bananas after harvest. Cinnamon oil was the most effective, successfully stopping all five types of harmful fungi at relatively low concentrations. The findings suggest these natural oils could replace harsh chemical fungicides used to preserve bananas during storage and transport, making banana production more environmentally friendly.

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One-Health Approach to Managing Aflatoxin-Producing Aspergillus flavus Using Spent Mushroom Substrate of Pleurotus spp

This study shows that leftover substrate from growing oyster and red mushrooms can work together with a common antifungal fungicide to better prevent harmful Aspergillus fungi from contaminating corn. The combination of mushroom waste and fungicide was more effective than using either alone, and could potentially reduce the amount of chemicals needed in agriculture while protecting the environment and preventing drug resistance.

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Isolation and identification of Fusarium species from the water systems of ICUs and transplant wards of hospitals and determination of the in vitro susceptibilities of isolates to conventional antifungals

Researchers found dangerous Fusarium fungal species in water systems of hospital ICU wards in Tehran, Iran. These fungi can spread through water fixtures and pose serious risks to patients with weak immune systems. Testing showed that certain antifungal drugs like posaconazole and voriconazole worked well against these fungi, but other drugs were less effective. The study emphasizes the importance of better water management and safety measures in hospitals to protect vulnerable patients.

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Humans vs. Fungi: An Overview of Fungal Pathogens against Humans

Fungal infections are serious health threats that kill approximately 1.5 million people annually worldwide. This comprehensive review identifies over 280 different fungal species that can infect humans, with Aspergillus being the most dangerous genus. The study provides updated information on how these infections are diagnosed through various methods including cultures, microscopy, and molecular testing, as well as treatment options ranging from traditional antifungal drugs to newer therapies like nanotechnology-based formulations.

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Mesoporous silica and vegetal extracts combined as sustainable stone heritage protection against biodeterioration

Researchers developed an eco-friendly method to protect historic stone buildings and sculptures from fungal damage. They trapped natural plant oils (from oregano and thyme) inside tiny nano-containers made of silica, which slowly releases the antimicrobial compounds over time. When tested on marble samples, this coating prevented fungal growth for two months without harmful chemicals, making it safe for both the environment and workers preserving cultural heritage.

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Impact of Clove Oil on Biofilm Formation in Candida albicans and Its Effects on Mice with Candida Vaginitis

This research demonstrates that clove oil, a natural and FDA-approved dietary supplement, can effectively combat Candida albicans infections that cause vaginal yeast infections. The study found that clove oil works by preventing the fungus from forming protective biofilms and by reducing inflammation. In mice with vaginal yeast infections, clove oil treatment significantly improved symptoms and reduced fungal levels, suggesting it could serve as a safer alternative to conventional antifungal medications.

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Cinchona-based liquid formulation exhibits antifungal activity through Tryptophan starvation and disruption of mitochondrial respiration in Rhizoctonia Solani

Researchers found that an extract from Cinchona bark, containing the compound quinine, effectively kills rice-damaging fungus Rhizoctonia solani through two mechanisms: starving the fungus of the amino acid tryptophan and disrupting its energy-producing mitochondria. This natural plant-based treatment could serve as an eco-friendly alternative to synthetic fungicides, reducing crop losses from fungal diseases while avoiding the environmental damage and resistance problems associated with chemical pesticides.

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The Efficacy of Clove Oil Against Aspergillus flavus and the Production of Aflatoxin B1 in Organic Peanuts in Georgia

Researchers tested clove essential oil as a natural antifungal treatment for peanuts infected with a mold that produces aflatoxin, a dangerous toxin harmful to human health. They found that clove oil significantly reduced both the mold growth and toxin production, with the best results at moderate concentrations. This discovery offers organic farmers an eco-friendly alternative to synthetic fungicides for protecting their peanut crops. The findings could help reduce a major agricultural problem that costs the Southeast millions of dollars annually.

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In Vitro Screening of the Antifungal and Antimycotoxin Effects of a Stilbenoids-Rich Grapevine Cane Extract on Fusarium graminearum, Aspergillus flavus and Penicillium expansum

Researchers tested an extract made from grapevine pruning waste to see if it could stop harmful fungi and the toxins they produce. The extract, rich in natural compounds called stilbenoids, successfully reduced growth and toxin production in three dangerous fungi that contaminate crops. The effects were strong enough that scientists believe this agricultural waste could become a natural alternative to chemical fungicides for protecting crops.

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