antifungal activity – Page 30

Characterization of a bacterial strain T226 and its efficacy in controlling post-harvest citrus anthracnose

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Researchers identified a beneficial bacterium called Lysobacter enzymogenes (strain T226) that effectively prevents citrus fruit rot caused by anthracnose fungus. This bacterium was isolated from soil and showed stable antimicrobial properties even after repeated culture transfers. When applied to citrus fruits, it reduced disease incidence by over 61% under natural storage conditions, performing better than the chemical fungicide prochloraz, making it a promising eco-friendly alternative for protecting stored citrus.

Cell Wall-Mediated Antifungal Activity of the Aqueous Extract of Hedera helix L. Leaves Against Diplodia corticola

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Scientists discovered that extract from ivy leaves can effectively kill a fungus called Diplodia corticola that damages cork oak trees. The extract works by damaging the fungus’s protective cell wall rather than interfering with its internal chemistry. This natural alternative to chemical fungicides could help protect cork production worldwide while being safer for human health and the environment.

Essential Oils as an Antifungal Alternative to Control Several Species of Fungi Isolated from Musa paradisiaca: Part II

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Bananas often develop fungal infections during storage that reduce their quality. Researchers tested whether essential oils from common herbs and spices like cinnamon, clove, and oregano could prevent these fungal infections. The study found that cinnamon, clove, and oregano oils effectively stopped fungal growth at higher concentrations, offering a natural alternative to chemical fungicides that could help keep bananas fresh longer without synthetic chemicals.

Comparative Antagonistic Activities of Endolichenic Fungi Isolated from the Fruticose Lichens Ramalina and Usnea

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Researchers studied fungi living inside lichen plants from the Philippines to see if they could help fight crop diseases. They tested 40 different fungi against three harmful pathogens that destroy important crops. The results showed that these lichen-dwelling fungi were effective at stopping pathogen growth, with fungi from Ramalina lichens performing better than those from Usnea lichens. This discovery suggests a natural, eco-friendly way to protect crops without harsh chemicals.

A mass spectrometry-based strategy for investigating volatile molecular interactions in microbial consortia: unveiling a Fusarium-specific induction of an antifungal compound

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Scientists developed a new method to study how different fungi communicate and compete with each other through invisible chemical signals called volatile organic compounds. By growing three types of fungi together in a controlled setup, they discovered that Fusarium culmorum specifically produces a compound called γ-terpinene when in contact with other fungi. This compound acts as a natural antifungal agent, helping Fusarium fight off competing fungi. This research provides a blueprint for understanding complex fungal interactions in environments like human lungs and could eventually help diagnose or prevent fungal-related diseases.

A Case of Superficial Mycoses in a Patient with Systemic Lupus Erythematosus

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A 52-year-old woman with lupus developed severe fungal skin infections that were initially mistaken for worsening lupus symptoms. Her condition improved after 6 months of treatment with two antifungal medications (terbinafine and itraconazole). This case reminds doctors that patients taking immunosuppressive medications for lupus are at high risk for fungal infections, which can be misdiagnosed as lupus flares.

Efficacy and safety of isavuconazole for invasive fungal infections: A systematic review and meta-analysis of randomized controlled trials

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This study reviewed clinical trials comparing a newer antifungal drug called isavuconazole with other commonly used antifungal medications for treating serious fungal infections, particularly in patients with weakened immune systems. The research found that isavuconazole works just as well as other antifungal drugs but may have fewer side effects, especially liver problems. When compared directly with voriconazole, isavuconazole showed fewer drug-related side effects overall, making it a good alternative option for patients who cannot tolerate other antifungal treatments.

A case of corneal infection with Clonostachys rosea

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A 53-year-old patient developed a serious eye infection caused by a fungus called Clonostachys rosea, which had never been reported before as causing eye disease. The infection caused a painful ulcer on the cornea (the clear front part of the eye). Doctors treated the infection with antifungal medications applied as eye drops and taken as tablets, and the patient recovered well within about a month.

Microbial-Based Green Synthesis of Silver Nanoparticles: A Comparative Review of Bacteria- and Fungi-Mediated Approaches

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Scientists are developing environmentally friendly ways to make silver nanoparticles using bacteria and fungi instead of harsh chemicals. These tiny particles show promise in fighting infections, treating cancer, cleaning water, and protecting crops. The review compares how bacteria and fungi each produce these particles and explains how different conditions affect their properties and effectiveness.

Eco-friendly biosynthesis of silver nanoparticles using marine-derived Fusarium equiseti: optimization, characterization, and evaluation of antimicrobial, antioxidant, and cytotoxic activities

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Scientists used a marine fungus called Fusarium equiseti to create tiny silver particles called nanoparticles in an environmentally-friendly way. These particles showed strong abilities to kill harmful bacteria and fungi, protect cells from damage caused by free radicals, and fight breast cancer cells in laboratory tests. This green synthesis method offers a safer, non-toxic alternative to traditional chemical manufacturing while producing stable, multi-functional nanoparticles.

therapeutic action: antifungal activity