antifungal activity – Page 11

Hass Avocado (Persea americana Mill) Peel Extract Reveals Antimicrobial and Antioxidant Properties against Verticillium theobromae, Colletotrichum musae, and Aspergillus niger Pathogens Affecting Musa acuminata Colla Species, in Ecuador

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Researchers tested whether avocado peel waste could help protect banana crops from fungal diseases. They extracted beneficial compounds from avocado peels and tested them against three harmful fungi that affect bananas. The results showed the extract worked best against one type of fungus and had good antioxidant properties, suggesting avocado peel could be a natural and sustainable way to protect banana crops.

Synergistic potential and apoptosis induction of Bunium persicum essential oil and its pure components, cuminaldehyde and γ-terpinene, in combination with fluconazole on Candida albicans isolates: in vitro and in silico evaluation

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Researchers studied how Bunium persicum essential oil and two of its active components work together with the antifungal drug fluconazole to fight resistant Candida yeast infections. They found that cuminaldehyde, one of the oil’s main components, was particularly effective when combined with fluconazole and could trigger yeast cell death. These natural compounds could offer a promising new approach to treating fungal infections that have become resistant to standard medications.

Transcriptome Analysis of Dimethyl Fumarate Inhibiting the Growth of Aspergillus carbonarius

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Researchers found that dimethyl fumarate, a chemical preservative, can effectively stop the growth of a common fruit fungus called Aspergillus carbonarius that causes rot and produces a harmful toxin in grapes. By studying how the fungus responds to this treatment at the genetic level, scientists discovered that the chemical damages the fungus’s protective outer layer and interferes with its ability to develop and reproduce. This research could lead to better ways to preserve fruit and prevent toxin contamination in the food industry.

Antifungal efficacy and mechanisms of Bacillus licheniformis BL06 against Ceratocystis fimbriata

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Researchers discovered that a beneficial bacterium called Bacillus licheniformis BL06 can effectively prevent sweet potato black rot, a fungal disease that causes major crop losses worldwide. When applied to sweet potatoes, this bacterium reduces disease damage by interfering with the fungus’s ability to grow, form spores, and survive. The study reveals that the bacterium works by disrupting the fungus’s cell structure and energy production, making it a promising natural alternative to chemical fungicides.

Essential Oils as an Antifungal Alternative for the Control of Various Species of Fungi Isolated from Musa paradisiaca: Part I

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Researchers tested six essential oils from common kitchen herbs to see if they could prevent banana spoilage caused by fungi. They found that cinnamon oil was especially effective, stopping fungal growth at relatively low concentrations. This research suggests that natural essential oils could replace harsh chemical fungicides in farming, making bananas safer for consumers and better for the environment.

Cinchona-based liquid formulation exhibits antifungal activity through Tryptophan starvation and disruption of mitochondrial respiration in Rhizoctonia Solani

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Scientists tested a plant-based extract from Cinchona bark as a natural fungicide against a serious fungus that damages rice crops. The active ingredient, quinine, works by two methods: it blocks the fungus from getting the amino acid tryptophan it needs to survive, and it damages the fungus’s energy-producing structures. When researchers added tryptophan back to the treated fungus, it recovered, confirming this is how the treatment works. This natural fungicide could offer farmers an eco-friendly alternative to chemical pesticides.

Terpinen-4-ol triggers autophagy activation and metacaspase-dependent apoptosis against Botrytis cinerea

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Terpinen-4-ol, a natural compound from tea tree oil, effectively kills gray mold fungus that spoils fruits and vegetables after harvest. The compound works by damaging fungal cell membranes, creating harmful reactive molecules inside fungal cells, and triggering the fungal cells’ self-destruction pathways. When tested on tomatoes and strawberries, terpinen-4-ol successfully reduced mold growth and disease spread, suggesting it could be a safe, eco-friendly alternative to chemical fungicides for protecting fresh produce.

Prospective Study on Microbiological Profile of Fungal Isolates and its Antibiogram in a Tertiary care hospital in South India

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Researchers studied fungal infections in a hospital in South India over one year, examining 62 fungal isolates. They found that Candida auris, a dangerous fungal species, was the most common and had developed resistance to many antifungal drugs. A newer class of antifungal drugs called echinocandins worked best against these infections, highlighting the importance of quick identification of fungal species for proper treatment.

An Efficient Microwave Synthesis of 3-Acyl-5-bromoindole Derivatives for Controlling Monilinia fructicola and Botrytis cinerea

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Scientists developed new chemical compounds called indole derivatives that can kill harmful fungi that destroy fruit crops like stone fruits and grapes. These compounds were made using microwave heating, which is faster and more efficient than traditional methods. Testing showed that some of these new compounds were even better at fighting these fungal diseases than current commercial fungicides, offering promise for protecting crops in agriculture.

Impact of Clove Oil on Biofilm Formation in Candida albicans and Its Effects on Mice with Candida Vaginitis

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Clove oil, a common kitchen spice, shows promise as a treatment for vaginal yeast infections caused by Candida albicans. The oil contains eugenol, which blocks the fungus’s ability to form protective biofilms and reduces inflammation. In mouse studies, clove oil treatment decreased yeast infection symptoms and lowered inflammatory markers, suggesting it could be a safe, natural alternative to conventional antifungal drugs.

therapeutic action: antifungal activity