therapeutic action: anticancer

Himalayan Mushrooms as a Natural Source of Ergosterol and Vitamin D2: A Review of Nutraceutical and Functional Food Perspectives

Mushrooms from the Himalayan region are naturally rich in ergosterol, a compound that converts to vitamin D2 when exposed to sunlight or UV light. This review explores how mushrooms can serve as sustainable, plant-based sources of vitamin D to address deficiencies in populations with limited sun exposure. By understanding how environmental factors and UV treatment affect ergosterol levels, scientists can develop enriched mushroom-based foods and supplements with enhanced nutritional benefits.

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Biodiversity-Driven Natural Products and Bioactive Metabolites

This comprehensive review explores how diverse organisms like plants, fungi, and marine creatures produce remarkable chemical compounds for survival and defense. These natural products have inspired many modern medicines, but scientists now understand that the chemical diversity comes not just from the organisms themselves but from their ecological interactions and environmental challenges. By studying how these chemicals are made and what triggers their production, researchers can discover new drugs and medicines while protecting the ecosystems that generate them.

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Morphological and Phylogenetic Characterization of Endophytic Fungi Isolated from Brown Algae (Phaeophyceae) in Korea

Researchers in Korea discovered three previously unknown fungal species living inside brown seaweed called Sargassum. These fungi were identified using genetic analysis and microscopy. The discovery suggests that seaweed hosts diverse fungal communities that could have useful properties, such as producing compounds with antimicrobial and anti-cancer potential. This research expands our understanding of marine fungal diversity and its possible applications in medicine and biotechnology.

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Recent Discoveries on Marine Organism Immunomodulatory Activities

Scientists are discovering that creatures from the ocean produce powerful substances that can help our immune system fight diseases like cancer and inflammation. These marine organisms—from tiny algae to sponges to fish—create natural compounds that can either boost or calm down our immune response depending on what we need. Several of these ocean-derived medicines are already approved for treating serious diseases, and many more are being tested in clinical trials. The ocean covers 70% of our planet and most of it remains unexplored, suggesting there are many more beneficial compounds waiting to be discovered.

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The Genus Cordyceps Sensu Lato: Their Chemical Constituents, Biological Activities, and Therapeutic Effects on Air Pollutants Related to Lung and Vascular Diseases

Cordyceps mushrooms have been used in traditional Chinese medicine for centuries and are now being studied scientifically for their potential health benefits. These mushrooms contain powerful compounds that may help protect our lungs from air pollution effects and support heart health. Recent clinical studies show promising results for treating conditions like COPD, asthma, and even improving athletic performance in healthy people.

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Biological Characteristics, Artificial Domestication Conditions Optimization, and Bioactive Components of Beauveria caledonica

Scientists successfully grew Beauveria caledonica mushrooms in a laboratory for the first time using wheat and rice as growing media. They identified the best growing conditions and found that these mushrooms contain beneficial compounds like polysaccharides and adenosine, which may have health benefits similar to traditional medicinal Cordyceps. The adenosine content was significantly higher than what is required by Chinese pharmacopoeia standards, suggesting these cultivated mushrooms could have strong medicinal value.

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Transcriptomic and metabolic profiling reveals adaptive mechanisms of Auricularia heimuer to temperature stress

Researchers studied how a popular edible mushroom called black wood ear (Auricularia heimuer) adapts to different temperatures. They found that the mushroom grows best at 35°C but struggles at very cold (15°C) or extremely hot (45°C) temperatures. By analyzing the genes and chemicals produced by the mushroom at different temperatures, scientists discovered that the mushroom uses different survival strategies depending on how hot or cold it is, which could help farmers grow better mushrooms.

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Nontargeted metabonomics analysis of Scorias spongiosa fruiting bodies at different growth stages

This study analyzed the chemical composition of Scorias spongiosa, an edible fungus, at different stages of growth using advanced laboratory techniques. Researchers found that the fungus contains beneficial compounds with antioxidant, anti-inflammatory, and other health-promoting properties. The study recommends harvesting the fungus at its earliest growth stage to preserve the most beneficial compounds for food and nutritional products.

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Advances in Fungal Natural Products: Insights into Bioactivity and Therapeutic Potential

Medicinal mushrooms and fungi contain powerful natural chemicals that can boost immunity, reduce inflammation, fight cancer, and protect the brain. Scientists are now better able to identify and study these compounds using advanced techniques, and some are being tested as supplements or alongside traditional medicines. This research shows that mushrooms could become important tools in treating diseases like inflammatory bowel disease, rheumatoid arthritis, and cancer.

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Enhancement and Mechanism of Ergosterol Biosynthesis in Termite Ball Fungus Athelia termitophila by Methyl Jasmonate

Scientists studied how to increase ergosterol production in termite ball fungus, a medicinal fungus used in traditional medicine. By adding methyl jasmonate, a natural signaling molecule, they more than doubled ergosterol content. Ergosterol is used to make vitamin D2 and certain medications for inflammation and cancer. The study identified which genes need to be activated for better ergosterol production, providing insights for creating more effective medical products from fungi.

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