therapeutic action: Antibiotic degradation

Impact of veterinary pharmaceuticals on environment and their mitigation through microbial bioremediation

Veterinary medicines used in livestock are contaminating our water and soil, creating serious problems like antibiotic-resistant bacteria. Scientists are discovering that natural microorganisms like bacteria and fungi can break down these pharmaceutical pollutants effectively. Advanced technologies combining microbes with electrical systems show promise for cleaning up contaminated wastewater, offering hope for a more sustainable solution to this growing environmental problem.

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Biotransformation of the Fluoroquinolone Antibiotic, Levofloxacin, by the Free and Immobilized Secretome of Coriolopsis gallica

Researchers discovered that a type of fungus called Coriolopsis gallica can break down the antibiotic levofloxacin, which persists in the environment and contributes to antibiotic resistance. They tested both free enzymes from the fungus and enzymes trapped in alginate beads to see which worked better. The study found that free enzymes degraded more of the antibiotic when a chemical helper molecule called HBT was added, while immobilized enzymes were more stable and could be reused multiple times.

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