therapeutic action: antibacterial effects

Biomimetic Nanotechnology Vol. 3

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Scientists are developing new technologies inspired by nature at extremely small scales to solve real-world problems. This collection showcases five innovative studies using mushrooms and plants to create nanoparticles, developing new treatments for heart disease, and creating smart materials that can detect harmful chemicals. These nature-inspired approaches are often safer, more sustainable, and more effective than traditional methods.

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Comparative Transcriptome Profiles of the Response of Mycelia of the Genus Morchella to Temperature Stress: An Examination of Potential Resistance Mechanisms

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Scientists studied how morel mushrooms respond to different temperatures to understand why cultivation can be unpredictable. By analyzing gene activity in mushroom mycelia (the underground filaments) at temperatures from 5°C to 30°C, they found that 15-20°C was ideal for growth. At higher temperatures, the mushrooms showed signs of stress similar to heat damage in other organisms, turning brownish and activating protective genes. This research helps mushroom farmers optimize growing conditions for better yields.

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The Effect of Topical Ketoconazole and Topical Miconazole Nitrate in Modulating the Skin Microbiome and Mycobiome of Patients With Tinea Pedis

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This study examined how two common antifungal creams (ketoconazole and miconazole) affect the complex community of bacteria and fungi living on the skin of people with athlete’s foot. Both treatments effectively reduced the harmful fungus causing the infection and improved symptoms, with ketoconazole working slightly faster. However, the researchers found that while these treatments reduced the disease-causing fungus, the skin’s normal microbial community did not fully recover to a healthy state, particularly in the spaces between the toes.

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Genome-Mining Based Discovery of Pyrrolomycin K and L from the Termite-Associated Micromonospora sp. RB23

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Scientists discovered two new antimicrobial compounds called pyrrolomycins from bacteria living in termites using genome sequencing and chemical analysis. These compounds contain chlorine atoms and are related to known antibiotics. The research shows how the bacteria protects itself from its own antimicrobial compounds through chemical modifications, offering insights into developing new antibiotics.

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Comparative Multi-Omics Analysis and Antitumor Activity of Phylloporia crataegi and Phylloporia fontanesiae

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Researchers compared two types of medicinal fungi (Phylloporia crataegi and Phylloporia fontanesiae) to understand why one is better at fighting cancer. They used advanced techniques to examine the fungi’s chemicals, genes, and proteins, discovering that P. crataegi contains special compounds like trans-cinnamic acid that help kill cancer cells. This study provides important information for developing new cancer treatments from these fungi.

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Comparative Multi-Omics Analysis and Antitumor Activity of Phylloporia crataegi and Phylloporia fontanesiae

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Researchers compared two types of medicinal fungi (Phylloporia crataegi and P. fontanesiae) to understand why one is more effective at fighting cancer. Using advanced molecular analysis techniques, they found that P. crataegi contains higher levels of cancer-fighting compounds and activates more genes related to cancer cell death. These findings suggest that these fungi could be promising sources for developing new cancer treatments.

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