therapeutic action: antibacterial activity

Microbial-Based Green Synthesis of Silver Nanoparticles: A Comparative Review of Bacteria- and Fungi-Mediated Approaches

Scientists have developed environmentally friendly ways to create tiny silver particles using bacteria and fungi instead of harsh chemicals. These silver nanoparticles can fight bacteria, help treat cancer, clean contaminated water, and improve food packaging. The review shows that bacteria produce particles quickly but fungi are better for large-scale production and create more stable particles.

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Novel secondary metabolite from a new species of Hypoxylon saxatilis sp. nov. for suppressing bacterial wilt in tomato

Researchers discovered a new fungus species (Hypoxylon saxatilis) living inside medicinal plants that produces a novel compound called tetrahydrofuran. This compound kills the bacterium that causes tomato wilt disease by damaging bacterial cell walls. In greenhouse tests, extract from this fungus reduced wilt disease severity by over 83%, suggesting it could be developed as an eco-friendly alternative to chemical pesticides for protecting tomato crops.

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Design, synthesis, and antimicrobial evaluation of novel 1,2,4-triazole thioether derivatives with a 1,3,4-thiadiazole skeleton

Scientists created 17 new chemical compounds that can fight harmful fungi and bacteria that damage plants. One of these compounds, called 9d, proved to be even more effective than existing commercial pesticides at fighting plant diseases. Tests on kiwifruit showed that this new compound could protect and treat bacterial infections better than currently available treatments. These new compounds could help protect crops and reduce reliance on older pesticides.

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Screening of Basidiomycete Strains Capable of Synthesizing Antibacterial and Antifungal Metabolites

Researchers tested 18 types of medicinal mushrooms to see if they could produce natural antibiotics. Most of them (16 out of 18) showed antimicrobial properties, with some being particularly effective against dangerous bacteria and fungi. The most promising mushroom strain (Hericium corraloides 4) showed strong activity against multiple disease-causing organisms. This research suggests that mushrooms could be valuable sources for developing new antibiotics to fight drug-resistant infections.

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Microbial-Based Green Synthesis of Silver Nanoparticles: A Comparative Review of Bacteria- and Fungi-Mediated Approaches

Scientists are developing environmentally friendly ways to make silver nanoparticles using bacteria and fungi instead of harsh chemicals. These tiny particles show promise in fighting infections, treating cancer, cleaning water, and protecting crops. The review compares how bacteria and fungi each produce these particles and explains how different conditions affect their properties and effectiveness.

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Strategies and materials for the prevention and treatment of biofilms

Biofilms are sticky communities of bacteria that form on medical devices and surfaces, making infections very difficult to treat with antibiotics. This review explains how biofilms develop in stages and describes different ways to stop them from forming or to destroy them once they exist. Solutions include special coatings on medical implants, natural plant extracts like essential oils, and engineered proteins called antimicrobial peptides that fight bacteria without creating antibiotic resistance.

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Saponins, the Unexplored Secondary Metabolites in Plant Defense: Opportunities in Integrated Pest Management

Plants naturally produce compounds called saponins that protect them from insects, fungi, bacteria, parasitic worms, and viruses. This review explains how saponins work as natural pest managers and discusses how plants rich in saponins, such as licorice and soapbark trees, could be used to develop environmentally friendly crop protection products instead of synthetic pesticides.

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Quest for Anti-SARS-CoV-2 antiviral therapeutics: in-silico and in-vitro analysis of edible mushroom- Cordyceps militaris

Researchers tested an edible mushroom called Cordyceps militaris to see if it could fight SARS-CoV-2, the virus that causes COVID-19. Using computer modeling and laboratory experiments, they found that a compound in the mushroom called cordycepin strongly attached to the virus’s spike protein and reduced viral numbers by about 50% in cell cultures. The study supports traditional uses of this mushroom and suggests it could be helpful in managing COVID-19 as the disease becomes endemic.

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Isolation, (bio)synthetic studies and evaluation of antimicrobial properties of drimenol-type sesquiterpenes of Termitomyces fungi

Termite colonies farm a fungus called Termitomyces for food in an ancient partnership. Scientists discovered that the mushrooms produced by this fungus release distinctive chemical signals, particularly a compound called drimenol. By isolating and synthesizing these compounds, researchers found they have antimicrobial properties and may play a role in communicating between termites and their fungal crop or protecting mushrooms from infection.

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Extracellular Biosynthesis, Characterization and Antimicrobial Activity of Silver Nanoparticles Synthesized by Filamentous Fungi

Researchers used three types of fungi to naturally create tiny silver particles that can kill harmful bacteria and fungi. These particles were much smaller than the width of a human hair and proved especially effective against dangerous bacteria like those causing hospital infections and Candida yeast infections. This green manufacturing method is safer for the environment than traditional chemical approaches and could help address the growing problem of drug-resistant infections.

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