therapeutic action: anti-tumor

Traditional uses, chemical components and pharmacological activities of the genus Ganoderma P. Karst.: a review

Ganoderma, a medicinal fungus used in traditional medicine for over 2000 years, contains many beneficial compounds including triterpenes and polysaccharides. Scientific research has confirmed its effectiveness in treating various conditions including cancer, diabetes, infections, and inflammation. The fungus works by boosting the immune system, reducing oxidative stress, and directly inhibiting disease-causing organisms. Modern cultivation methods have made Ganoderma products widely available as supplements and medicines worldwide.

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Influence of Culture Conditions on Bioactive Compounds in Cordyceps militaris: A Comprehensive Review

Cordyceps militaris is a medicinal fungus that produces powerful health-promoting compounds used to boost energy, strengthen immunity, and fight cancer. This review explains how different growing conditions—like the type of food the fungus is grown on, light exposure, and temperature—affect which beneficial compounds it produces and how much. By optimizing these conditions, producers can create more effective products for health supplements and medicines, though more research is needed to standardize production methods.

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Insights into the Mycosphere Fungal Community and Its Association with Nucleoside Accumulation in Ophiocordyceps sinensis

Chinese cordyceps (Ophiocordyceps sinensis) is a precious medicinal fungus found on the Tibetan Plateau that has anti-inflammatory and anti-tumor properties. Researchers studied the fungi living in soil around wild cordyceps and found that the types and amounts of these soil fungi are connected to how much medicinal compounds accumulate in the cordyceps. Samples from certain regions like Yushu had more diverse soil fungi and higher levels of beneficial compounds called nucleosides. This suggests that managing soil fungi could help improve the quality of cordyceps grown in cultivation.

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Biodegradation of ramie stalk by Flammulina velutipes: mushroom production and substrate utilization

This study shows that mushroom farmers can use ramie plant stalks, which are normally considered waste from textile production, as a growing substrate for golden needle mushrooms (Flammulina velutipes). By mixing ramie stalk with other common ingredients like wheat bran and cottonseed hulls in the right proportions, researchers achieved mushroom yields higher than using traditional substrates alone. This discovery helps reduce farming costs while solving an environmental waste disposal problem.

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Identifying the “Mushroom of Immortality”: Assessing the Ganoderma Species Composition in Commercial Reishi Products

Researchers tested 37 reishi mushroom products and kits sold in the United States and found that most were mislabeled. While products claimed to contain Ganoderma lucidum, over 93% of manufactured products actually contained Ganoderma lingzhi, a different Asian species. The study discovered that 86% of products tested contained something other than what the label claimed, which matters because different Ganoderma species have different chemical compositions and potentially different health benefits.

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Enhancement and Mechanism of Ergosterol Biosynthesis in Termite Ball Fungus Athelia termitophila by Methyl Jasmonate

Scientists studied how to increase ergosterol production in termite ball fungus, a medicinal fungus used in traditional medicine. By adding methyl jasmonate, a natural signaling molecule, they more than doubled ergosterol content. Ergosterol is used to make vitamin D2 and certain medications for inflammation and cancer. The study identified which genes need to be activated for better ergosterol production, providing insights for creating more effective medical products from fungi.

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Purification, Structural Characteristics, Bioactive Properties, and Applications of Naematelia aurantialba Polysaccharides: A Comprehensive Review

Golden ear (Naematelia aurantialba) is a traditional Chinese medicinal mushroom recently approved as a cosmetic ingredient. This comprehensive review examines how scientists extract and purify beneficial compounds called polysaccharides from this fungus, which can help manage blood sugar, boost immunity, reduce inflammation, and protect against oxidative damage. The mushroom shows promise as a natural ingredient for foods, supplements, and skincare products with potential health benefits.

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Exploring the Mechanisms of Amino Acid and Bioactive Constituent Formation During Fruiting Body Development in Lyophyllum decastes by Metabolomic and Transcriptomic Analyses

This study examined how Lyophyllum decastes mushrooms develop and build up their nutritious compounds. Researchers tracked amino acids and polysaccharides across four growth stages and identified which genes control their production. The mature mushrooms contained the highest levels of beneficial compounds, with amino acids reaching 45,107.39 μg/g and polysaccharides at 13.66 mg/g. These findings help explain why these mushrooms are nutritious and suggest ways to grow them better for maximum health benefits.

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Purification, Structural Characteristics, Bioactive Properties, and Applications of Naematelia aurantialba Polysaccharides: A Comprehensive Review

Golden ear (Naematelia aurantialba) is a traditional Chinese fungus that is becoming increasingly popular for its health benefits. This comprehensive review explains how scientists extract and purify the beneficial polysaccharides from golden ear, and what makes them effective against diseases like diabetes and inflammation. The research shows these mushroom polysaccharides could be used in medicines, functional foods, and even cosmetics to improve human health.

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Metabolomics analysis of mycelial exudates provides insights into fungal antagonists of Armillaria

This study examined how two types of honey mushrooms (Armillaria) fight each other when grown together. Researchers found specific chemical markers and metabolic pathways that are activated during this competition. The study identified 156 new compounds produced during co-culture, including 32 with potential antifungal properties. These findings could help understand how mushrooms naturally combat fungal pathogens.

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