therapeutic action: anti-tumor properties

A Combination of Transcriptome and Enzyme Activity Analysis Unveils Key Genes and Patterns of Corncob Lignocellulose Degradation by Auricularia heimuer under Cultivation Conditions

Researchers investigated using corncob, a corn industry byproduct, as a growing medium for Auricularia heimuer mushrooms instead of expensive sawdust. By analyzing which genes the mushroom activates at different growth stages, they identified key enzymes responsible for breaking down corncob’s tough cellulose structure. The findings show the mushroom can effectively adapt to use corncob as a substrate, offering a sustainable and economical alternative for mushroom farming while reducing agricultural waste.

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Chromosome-Scale Genome and Transcriptomic Analyses Reveal Differential Regulation of Terpenoid Secondary Metabolites in Hericium coralloides

Researchers sequenced the complete genome of Hericium coralloides, an edible medicinal mushroom, at the chromosome level for the first time. They identified genes responsible for producing terpenoids, which are beneficial compounds with antioxidant, anti-inflammatory, and anti-tumor properties. The study found that these beneficial compounds are produced in higher amounts in the mushroom’s mycelium (root-like structure) compared to fruiting bodies, which could help optimize mushroom cultivation for medicinal use.

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Multiomics Provides a New Understanding of the Effect of Temperature Change on the Fermentation Quality of Ophiocordyceps sinensis

This research studied how temperature affects the growth and quality of Ophiocordyceps sinensis, a valuable medicinal fungus. Scientists found that the fungus grows best between 18-23°C, and that temperatures above 28°C damage the fungus by triggering cell death processes. The study identified which genes and metabolites are affected by temperature changes, helping optimize large-scale production of this medicinal fungus.

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