therapeutic action: anti-tumor activity

The Soil Bacterial Community Structure in a Lactarius hatsudake Tanaka Plantation during Harvest

Researchers studied the soil bacteria in Lactarius hatsudake mushroom plantations to understand which bacteria help these valuable mushrooms grow. They found that mushroom-producing areas had different and less diverse bacterial communities compared to control areas, with specific bacteria like Burkholderia species being particularly abundant. These beneficial bacteria appear to create a stable environment that supports mushroom development, which could help improve mushroom farming practices in the future.

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Biological Activities of Secondary Metabolites from the Edible-Medicinal Macrofungi

This comprehensive review examines over 270 bioactive compounds from edible and medicinal mushrooms, showing they have remarkable potential to treat various diseases. These mushroom-derived substances demonstrate effectiveness against cancer, diabetes, inflammation, and infections while having fewer side effects than conventional drugs. Families like reishi and shiitake mushrooms are particularly rich sources of these healing compounds. The research suggests mushrooms are valuable natural resources for developing new therapeutic treatments.

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Soy Sauce Fermentation with Cordyceps militaris: Process Optimization and Functional Profiling

Researchers created a new type of soy sauce using Cordyceps militaris fungus, which contains health-promoting compounds. Using scientific optimization techniques, they found the best conditions for fermentation, resulting in a soy sauce with much higher levels of cordycepin and other beneficial compounds compared to traditional soy sauce. This product offers both the familiar taste of soy sauce and added health benefits, potentially serving as a functional food that people can use daily.

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Transcriptomic Profiling of Thermotolerant Sarcomyxa edulis PQ650759 Reveals the Key Genes and Pathways During Fruiting Body Formation

Researchers studied how a special strain of Sarcomyxa edulis (a tasty edible mushroom from Northeast China) develops fruiting bodies by analyzing which genes are turned on and off during this process. By comparing immature mycelium with developing fruiting bodies, they identified key genes responsible for cell division, DNA repair, and energy metabolism that control fruiting body formation. This knowledge can help mushroom farmers improve yield and quality through better understanding of how mushrooms grow. The findings provide a foundation for developing better cultivation techniques and selecting superior mushroom strains for commercial production.

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Study on Optimization of Liquid Fermentation Medium and Antitumor Activity of the Mycelium on Phyllopora lonicerae

Scientists optimized how to grow Phylloporia lonicerae fungus in the lab, increasing its production by 142% while cutting growth time by two-thirds. They discovered that certain compounds extracted from this fungus, particularly from a petroleum ether extract, can kill cancer cells and trigger apoptosis. The petroleum ether extract was more effective than the standard cancer drug 5-fluorouracil, especially against esophageal cancer cells, suggesting this fungus could be developed into a natural anti-cancer treatment.

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Study on Optimization of Liquid Fermentation Medium and Antitumor Activity of the Mycelium on Phyllopora lonicerae

Researchers improved the production of a medicinal fungus called Phylloporia lonicerae that grows on honeysuckle plants. They developed a better growing medium that produced more fungus in less time. They then discovered that components from this fungus can kill cancer cells, particularly lung and esophageal cancer cells, by triggering a natural cell death process called apoptosis. This work suggests the fungus could be developed into an anti-cancer functional food.

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Extraction, purification, and identification of total saponins from hazel mushroom and its application evaluation

Researchers developed an efficient method to extract beneficial compounds called saponins from hazel mushrooms using microwaves. They identified 22 different chemical compounds in these extracts and tested their effects on cancer cells and oxidative stress. The saponin extracts significantly inhibited the growth of lung cancer and bone cancer cells and demonstrated antioxidant properties, suggesting hazel mushrooms could be developed into functional foods or medicines.

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