anti-inflammatory – Page 4

The Role of Wolfiporia cocos (F. A. Wolf) Ryvarden and Gilb. Polysaccharides in Regulating the Gut Microbiota and Its Health Benefits

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Wolfiporia cocos, a fungus used in traditional Chinese medicine for over 2000 years, contains polysaccharides that act as prebiotics to improve gut health. These polysaccharides promote the growth of beneficial bacteria while inhibiting harmful ones, increase production of healthy metabolites, and strengthen the intestinal barrier. By improving gut microbiota composition, these polysaccharides can help prevent and treat various diseases including obesity, diabetes, and inflammatory conditions.

Indole-Based Compounds as Potential Drug Candidates for SARS-CoV-2

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Scientists are searching for new treatments for COVID-19 by studying indole-containing compounds, which are found in many plants and can be made in laboratories. Some approved drugs with indole structures, like the antiviral drug Arbidol, have been repurposed to fight COVID-19. Researchers are also designing new indole compounds and using computer simulations to predict which ones might work best against the virus’s key proteins.

Bioactive Metabolites from the Fruiting Body and Mycelia of Newly-Isolated Oyster Mushroom and Their Effect on Smooth Muscle Contractile Activity

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Researchers isolated a new oyster mushroom strain and studied how it affects digestive system health. They compared the fruiting body and mycelium (root-like structure) and found that water extracts of the fruiting body were rich in beneficial compounds like β-glucans and antioxidants. When tested on stomach muscle tissue, these extracts caused muscle contractions in a dose-dependent manner, suggesting potential benefits for digestive function. This discovery could lead to new natural supplements supporting gut health.

Changes of Active Substances in Ganoderma lucidum during Different Growth Periods and Analysis of Their Molecular Mechanism

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Scientists studied how the medicinal mushroom Ganoderma lucidum changes as it grows, discovering that different growth stages contain different beneficial compounds. The budding stage was found to have the highest levels of powerful healing compounds called triterpenoids and steroids. This research helps identify the best time to harvest the mushroom to get maximum health benefits, improving both quality and standardized production for medicinal use.

Fractionation of Saffron (Crocus sativus L.) Extract by Solid-Phase Extraction and Subsequent Encapsulation in Liposomes Prepared by Reverse-Phase Evaporation

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Saffron is a valuable spice with powerful health benefits, but its beneficial compounds break down easily and don’t absorb well when eaten. This research developed a special two-step process to extract and purify saffron’s active ingredients, then encapsulated them in tiny fatty spheres called liposomes to protect them in the stomach and improve absorption. The results show that liposomes can effectively trap the beneficial saffron compounds, making them more stable and more likely to reach the tissues where they’re needed.

Evaluation of Lipid Changes During the Drying Process of Cordyceps sinensis by Ultra Performance Liquid Chromatography–Tandem Mass Spectrometry (UPLC-MS/MS)-Based Lipidomics Technique

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This study examines how different drying methods affect the lipid content of Cordyceps sinensis, a valuable medicinal mushroom. Researchers compared three drying techniques—freeze-drying, oven-drying, and air-drying—and found that freeze-drying best preserves the mushroom’s beneficial lipids, while oven-drying causes significant degradation. The findings provide practical guidance for mushroom producers on selecting optimal drying methods to maintain the medicinal quality and nutritional value of this prized fungus.

Therapeutic Potential of Bioactive Compounds in Edible Mushroom-Derived Extracellular Vesicles: Isolation and Characterization of EVs from Pleurotus eryngii

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Researchers isolated tiny particles called extracellular vesicles (EVs) from a medicinal mushroom called king oyster mushroom (Pleurotus eryngii). These EVs act like natural delivery packages containing beneficial compounds like antioxidants and anti-inflammatory molecules. The study found that EVs from mushroom mycelium (the root-like part) were purer and more potent than those from the mushroom cap, with strong abilities to neutralize harmful free radicals in the body.

Synergy of de-walled Ganoderma Lucidum spore powder (GLSP) on targeted therapy in advanced non-squamous non-small cell lung cancer with epidermal growth factor receptor (EGFR) mutant: protocol for a randomized, double-blind, placebo-controlled study

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This study tests whether Ganoderma lucidum spore powder, a traditional Chinese medicine supplement, can help reduce fatigue in lung cancer patients taking the drug Osimertinib. Fatigue is a major side effect that affects most patients on this medication. The 140-patient trial compares patients receiving the supplement plus Osimertinib with those receiving a placebo plus Osimertinib, measuring fatigue levels and quality of life over 8 weeks.

Use of Medicinal Mushrooms in Layer Ration

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This review discusses how medicinal mushrooms can be added to chicken feed to improve egg production and boost chicken health, offering a natural alternative to antibiotics. Several types of mushrooms like shiitake and oyster mushrooms have been shown to increase egg quality, strengthen immunity against diseases, and reduce cholesterol in eggs. These findings support the use of mushrooms as a sustainable solution for organic egg farming without compromising production or health.

The Silent Revolution of Brewer’s Spent Grain: Meat/Food Innovations Through Circularity, Resource Recovery, and Nutritional Synergy—A Review

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Brewer’s spent grain is a leftover from beer production that can be transformed into nutritious ingredient for meat products and other foods. When added to burgers and sausages, it increases protein and fiber content while reducing fat, making healthier versions of these foods without sacrificing taste. This approach helps reduce food waste from breweries while providing consumers with more nutritious meat products in a sustainable way.

therapeutic action: anti-inflammatory