therapeutic action: anti-inflammatory

Regulatory effects of Poria cocos polysaccharides on gut microbiota and metabolites: evaluation of prebiotic potential

Poria cocos is a medicinal mushroom commonly used in Asian cuisine and traditional medicine. This study found that its polysaccharides act as prebiotics by feeding beneficial gut bacteria like Lactobacillus and Bifidobacterium while reducing harmful bacteria. The fermentation produces beneficial compounds called short-chain fatty acids that support digestive health and may help prevent diseases like obesity and inflammation.

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Olive mill solid waste induces beneficial mushroom-specialized metabolite diversity revealed by computational metabolomics strategies

This study shows how adding olive mill waste to mushroom growing substrate can increase beneficial compounds in mushrooms while reducing harmful toxins. Researchers grew two types of edible mushrooms (lion’s mane and king oyster) on substrate containing different amounts of olive mill waste and used advanced chemical analysis to identify how the waste affected the mushrooms’ medicinal compounds. Adding olive mill waste increased healthy compounds like hericenones and erinacerins while decreasing toxic enniatin compounds, potentially creating safer and more nutritious mushrooms for consumers.

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A multilocus phylogeny of Hericium (Hericiaceae, Russulales)

Researchers conducted the first comprehensive genetic study of lion’s mane mushrooms (Hericium species) using advanced DNA sequencing techniques. The study resolved long-standing confusion about different species and their relationships, while also describing a new species from western North America. These mushrooms are prized both as food and for traditional medicinal uses, particularly in Asia, and contain compounds with potential anti-inflammatory, antimicrobial, and neuroprotective properties. Better identification of species will help both commercial cultivators and medical researchers work with the correct organisms.

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Comparative evaluation of free radical scavenging activity and total metabolite profiles among 30 macrofungi species

This study tested 30 different mushroom species to determine which ones are the best sources of natural antioxidants that can help protect the body from damage caused by harmful free radicals. Researchers grew the mushrooms in laboratory conditions and measured their antioxidant power and beneficial compounds like polyphenols and polysaccharides. Oyster-like mushrooms called Lentinula edodes and Fomitopsis pinicola showed the strongest antioxidant activity, making them promising candidates for use in health supplements and functional foods.

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Potential Cosmetic Applications of the Combined Extract of Panax ginseng, Ganoderma lucidum, Cordyceps militaris, and Several Asian Plants

Researchers created a combination extract from four Asian plants including ginseng, medicinal mushrooms, and other herbs to treat acne. They tested this blend in laboratories and found it effectively killed acne-causing bacteria, reduced skin inflammation, repaired the skin barrier, and reduced oily skin production. The extract was safe for skin cells and appeared to work as well as or better than standard treatments.

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Medicinal Mushrooms as Multicomponent Mixtures—Demonstrated with the Example of Lentinula edodes

Shiitake mushrooms are more than just tasty food—they contain numerous compounds that work together to improve health. Unlike single isolated drugs, whole mushroom preparations offer multiple benefits including boosting immunity, protecting the heart, and potentially supporting cancer treatment. These mushrooms have been used safely in Asian medicine for over 2000 years and are becoming recognized worldwide for their health-promoting properties.

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The Antioxidant Properties of Mushroom Polysaccharides can Potentially Mitigate Oxidative Stress, Beta-Cell Dysfunction and Insulin Resistance

This research review explores how mushroom compounds called polysaccharides may help manage diabetes by reducing harmful stress on cells caused by high glucose levels. Scientists found that 104 different mushroom polysaccharides have anti-diabetic properties and can protect insulin-producing cells in the pancreas. These natural compounds show promise as a complementary treatment to conventional diabetes medications, potentially with fewer side effects than synthetic drugs.

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Scrutinizing the Nutritional Aspects of Asian Mushrooms, Its Commercialization and Scope for Value-Added Products

Mushrooms are nutrient-dense foods that can help address malnutrition and provide health benefits comparable to meat and eggs. They contain proteins, vitamins, minerals, and special compounds that help fight inflammation, boost immunity, and prevent diseases like cancer and heart disease. Mushroom-based products like powders, capsules, and fortified foods are becoming increasingly available in markets, offering practical ways to incorporate these nutritional benefits into daily diets.

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Metabolomics Profiling of White Button, Crimini, Portabella, Lion’s Mane, Maitake, Oyster, and Shiitake Mushrooms Using Untargeted Metabolomics and Targeted Amino Acid Analysis

Researchers analyzed seven popular mushroom varieties to understand their chemical makeup. They found over 10,000 different compounds across all mushrooms, with each variety having its own unique set of chemicals. Lion’s mane and oyster mushrooms were particularly rich in L-ergothioneine, a special amino acid thought to have antioxidant and anti-aging properties. The common white button, crimini, and portabella mushrooms had similar nutrient profiles, while specialty mushrooms had distinct chemical signatures.

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Freeze-Dried Probiotic Fermented Camel Milk Enriched with Ajwa Date Pulp: Evaluation of Functional Properties, Probiotic Viability, and In Vitro Antidiabetic and Anticancer Activities

Researchers created a powdered functional food by combining fermented camel milk with Ajwa date pulp and probiotics. The product showed promise in helping manage blood sugar levels and fighting cancer cells in laboratory tests. Adding date pulp improved the powder’s ability to mix with water and helped beneficial bacteria survive digestion. This combination of camel milk and dates offers a potential new functional food option for people looking to prevent or manage diabetes and other diseases.

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